In GranderLab/miR34a_asRNA_project: The miR34AasRNAproject package facilitates the transparency and reproducibility of the miR34a asRNA project and associated publication.

packages <- c(
    "tidyverse",
    "printr",
    "ggthemes",
    "readr",
    "miR34AasRNAproject",
    "grid",
    "gtable"
)
purrr::walk(packages, library, character.only = TRUE)
rm(packages)

projectUrl <- "https://github.com/GranderLab/miR34a_asRNA_project/raw/master/inst"
dataUrl <- "https://github.com/GranderLab/miR34a_asRNA_project/raw/master/"

Introduction

An antisense transcript to the miR34a HG was detected using the UCSC genome browser.

Methods

The USCS genome browser was utilized for the bioinformatic evaluation of antisense transcription at the miR34a locus.

Results

url <- fileMap(type = "png")["Figure 1a"][[1]]
knitr::include_graphics(file.path(projectUrl, url))

A schematic picture of the miR34a locus from the UCSC genome browser (hg38) including miR34a HG and mature miR34a, and LINC01759. H3K4me3 ChIP-seq and conservation over the locus is also shown.

Conclusion

Refseq annotation supports the presence of a transcript orininating in the antisense orientation from the miR34a gene.

sessionInfo()

GranderLab/miR34a_asRNA_project documentation built on May 26, 2019, 7:26 a.m.