inst/tinytest/test_groupComparisonPTM.R

In Vitek-Lab/MSstatsPTM: Statistical Characterization of Post-translational Modifications

data("summary.data", package = "MSstatsPTM")
data("summary.data.tmt", package = "MSstatsPTM")

## Test missing data is handled
expect_error(groupComparisonPTM())
expect_error(groupComparisonPTM(list(PTM = NULL, 
                                     PROTEIN = summary.data$PROTEIN), 
                                data.type = "LabelFree"))

expect_silent(groupComparisonPTM(list(PTM = summary.data$PTM, 
                                     PROTEIN = NULL), 
                                data.type = "LabelFree"))

## Test expected output - LF
group.comp <- MSstatsPTM::groupComparisonPTM(summary.data, 
                                             data.type = "LabelFree")
expect_inherits(group.comp, "list")
expect_inherits(group.comp$PTM.Model, "data.table")
expect_inherits(group.comp$PROTEIN.Model, "data.table")
expect_inherits(group.comp$ADJUSTED.Model, "data.table")

expect_equal(colnames(group.comp$PTM.Model), 
             c("Protein", "Label", "log2FC", "SE", "Tvalue", "DF", "pvalue",
               "adj.pvalue", "issue", "MissingPercentage", 
               "ImputationPercentage"))
expect_equal(colnames(group.comp$PROTEIN.Model), 
             c("Protein", "Label", "log2FC", "SE", "Tvalue", "DF", "pvalue",
               "adj.pvalue", "issue", "MissingPercentage", 
               "ImputationPercentage"))
expect_equal(colnames(group.comp$ADJUSTED.Model), 
             c("Protein", "Label", "log2FC", "SE", "Tvalue", "DF", "pvalue", 
               "adj.pvalue", "GlobalProtein", "Adjusted"))

## Test expected output - TMT
group.comp.tmt <- MSstatsPTM::groupComparisonPTM(summary.data.tmt, 
                                                 data.type = "TMT")
expect_inherits(group.comp.tmt, "list")
expect_inherits(group.comp.tmt$PTM.Model, "data.table")
expect_inherits(group.comp.tmt$PROTEIN.Model, "data.table")
expect_inherits(group.comp.tmt$ADJUSTED.Model, "data.table")

expect_equal(colnames(group.comp.tmt$PTM.Model), 
             c("Protein", "Label", "log2FC", "SE", "DF", "pvalue", 
               "adj.pvalue", "issue"))
expect_equal(colnames(group.comp.tmt$PROTEIN.Model), 
             c("Protein", "Label", "log2FC", "SE", "DF", "pvalue", 
               "adj.pvalue", "issue"))
expect_equal(colnames(group.comp$ADJUSTED.Model), 
             c("Protein", "Label", "log2FC", "SE", "Tvalue", "DF", "pvalue", 
               "adj.pvalue", "GlobalProtein", "Adjusted"))