YosefLab/LineagePulse: Differential expression analysis and model fitting for single-cell RNA-seq data

LineagePulse is a differential expression and expression model fitting package tailored to single-cell RNA-seq data (scRNA-seq). LineagePulse accounts for batch effects, drop-out and variable sequencing depth. One can use LineagePulse to perform longitudinal differential expression analysis across pseudotime as a continuous coordinate or between discrete groups of cells (e.g. pre-defined clusters or experimental conditions). Expression model fits can be directly extracted from LineagePulse.

Getting started

Package details

Bioconductor views CellBasedAssays CellBiology DifferentialExpression GeneExpression ImmunoOncology Sequencing SingleCell Software StatisticalMethod TimeCourse
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
YosefLab/LineagePulse documentation built on May 6, 2019, 2:19 p.m.