find_group_marker_genes: Find group-specific genes.

View source: R/differential_state.R

find_group_marker_genesR Documentation

Find group-specific genes.

Description

Find group-specific genes.

Usage

find_group_marker_genes(
  sce,
  pb,
  target_group,
  method = c("edgeR", "DESeq2", "limma-trend", "limma-voom")
)

Arguments

sce

A SingleCellExperiment object. The following cell metadata (colData) columns have to be provided:

sample_id

unique sample identifiers

cluster_id

subpopulation (cluster) assignments

group_id

experimental group/condition

pb

Object return by calculate_pseudo_bulk

target_group

Which group to find marker genes.

method

Specify which bulk RNA-seq DE methods to apply.


altairwei/rhapsodykit documentation built on Feb. 1, 2023, 8:52 a.m.