bic.get.deseq.cds: Normalize raw count matrix using DESeq scaling method

Description Usage Arguments Value

Description

Normalize raw count matrix using DESeq scaling method

Usage

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bic.get.deseq.cds(raw.counts, conds, min.count = 10, libsizeQ = F,
  percentile = "100%", fitType = "parametric", method = "per-condition",
  sharingMode = "maximum")

Arguments

raw.counts

Raw count matrix, where each column is a sample and each row is a gene

conds

vector of sample conditions, in the same order as column names in raw.counts

min.count

minimum total number of reads for a gene across samples; Default: 10

libsizeQ

logical to indicate we should use library size to normalize counts rather than DESeq's method [TO DO: RECHECK THIS]

percentile

string indicating percentile to use when normalizing by library size

fitType

See DESeq documentation. Default: "parameteric"

method

See DESeq documentation. Default: "per-condition"

sharingMode

See DESeq documentation. Default: "maximum"

Value

DESeq's countDataSet object


bic-mskcc/bicrnaseq documentation built on May 24, 2019, 3:04 a.m.