cnvScoreStouffer: Integrate CNV scores

In califano-lab/MOMA: Multi Omic Master Regulator Analysis

Description

Integrate CNV scores

Usage

cnvScoreStouffer(
  mapping,
  diggit.interactions,
  cytoband = TRUE,
  from.p = FALSE,
  pos.nes.only = TRUE
)

Arguments

mapping	a named vector of genomic locations/cytoband IDs. names are the gene names for each–i.e. a many to one mapping from HUGO or entrez IDs to cytoband location
diggit.interactions	list indexed by MR/TF name in Entrez Space each points to a named vector of NES / z-scores associated with entrez IDs for each interacting event.
cytoband	Boolean to use cytoband locations for computing final integrated score
from.p	Boolean, set TRUE if diggit.interaction values are p-values instead of z-scores
pos.nes.only	Boolean, only consider positive DIGGIT association scores when ranking candidate MRs (default=TRUE)

Value

A vector of z-scores, named by the Master Regulators in 'diggit.interactions'

califano-lab/MOMA documentation built on June 7, 2020, 7:17 a.m.