subgroup_specific_genomic_regions: Find subgroup specific regions

In eilslabs/epic: Integrative Analysis and Visualization of Epigenomic Sequencing Data

Description

Find subgroup specific regions

Usage

subgroup_specific_genomic_regions(gr, factors,
    present = 0.7, absent = 0.3, type = NULL)

Arguments

gr	a GRanges object generated by common_regions
factors	classifications which correspond to samples in gr
present	how to define a common region that is specifically present in one subgroup. The subgroup specificity is calculated based on the precent matrix stored in gr. For each subgroup which is defined in factors, if present is a single numeric value, it means the mean value should be larger than this. It can also be a function for which the input is the vector of percent in corresponding subgroup and the output should be a single logical value.
absent	how to define a common region is specifically absent in one subgroup. Format is same as present
type	It uses a string containing 1 and 0 to represent types of specificity. E.g. '1100' means present in subgroup 1 and 2 while absent in subgroup 3 and 4. By default, it will output all combination of subgroup specificities.

Value

This function splits the original gr into a list in which each element contains regions corresponding to different subgroup specificity.

Author(s)

Zuguang Gu <[e-mail]>

See Also

The returned value can be sent to plot_subgroup_specificity_heatmap to visualize the specificity.

Examples

# There is no example
NULL

eilslabs/epic documentation built on May 16, 2019, 1:24 a.m.