README.md

exprsex

E Flynn and Annie Chang

R package for sex labeling expression data. Still beta version.

To install, in R 1. Install three Bioconductor packages for data mapping: BiocManager::install(c("org.Hs.eg.db", "org.Rn.eg.db", "org.Mm.eg.db")) 2. Make sure you have devtools installed and loaded, then run: devtools::install_github(erflynn/exprsex). This will also prompt you to install the required dependencies.

To run: 1. Download an expression dataset using getPrepGSE(gse) 2. Prepare the input by running: reorderRank(expr) 3. Then, either: * Train a sex labeler: fit <- trainSexLab(expr, sex_lab) * Or run sex labeling: predSexLab(fit, expr)

Sex labeling genes are from ISEXs (Bongen et al., in preparation).



erflynn/exprsex documentation built on Jan. 26, 2020, 10:07 a.m.