ccr.genes2sgRNAs: Targeting sgRNAs

In francescojm/CRISPRcleanR: Unsupervised correction of gene independent cell responses to CRISPR-cas9 targeting

Targeting sgRNAs

Description

This function returns the set of sgRNAs targeting the set of genes provided in input, in a given pooled library.

Usage

ccr.genes2sgRNAs(libraryAnnotation,genes)

Arguments

libraryAnnotation	A data frame with a named row for each sgRNA with the same format of KY_Library_v1.0
genes	A list of strings containing HGNC symbols

Value

A list of strings containing the identifiers of the sgRNAs targeting the inputted set of genes

Author(s)

Francesco Iorio ([e-mail])

See Also

KY_Library_v1.0

Examples

    ## Loading an sgRNA pooled library annotation
    data(KY_Library_v1.0)
    ## Loading an example set of genes
    data(BAGEL_essential)
    
    ccr.genes2sgRNAs(KY_Library_v1.0,BAGEL_essential)

francescojm/CRISPRcleanR documentation built on April 30, 2023, 5:41 a.m.