ASCN.SEQUENZA: Allele-Specific Copy Number estimation using SEQUENZA

Description Usage Arguments Value Author(s)

View source: R/EaCoN_functions.R

Description

This function performs the estimation of allele-specific copy number using SEQUENZA.

Usage

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  ASCN.SEQUENZA(data = NULL, max.ploidy = 4, ploidy.step = .1,
  seg.min.size = 1E+06, out.dir = getwd(), force = FALSE)

Arguments

data

Data object contained in a RDS file generated with Segment.SEQUENZA() (or corresponding wrappers Segment.ff() and Segment.ff.Batch(), using the "FACETS" segmenter.

max.ploidy

Maximal median ploidy value to evaluate.

ploidy.step

Step for the ploidy value to evaluate in loop.

seg.min.size

Minimal size (in nt) of a segment to be used in the model fit.

out.dir

Output directory.

force

If some result files already exist, delete them before runing.

Value

Several RDS objects, PNG plots, CBS files and data tables.

Author(s)

Bastien Job


gustaveroussy/EaCoN documentation built on Oct. 20, 2021, 2:41 a.m.