README.md

Combined MR-Coloc Pipeline

This package combines Mendelian randomisation (MR) and colocalisation (coloc) with the aim of providing causal evidence between exposure-outcome pairs. The pipeline favours molecular data as exposure, for example, gene expression or protein abundance quantitative trait loci (QTLs), but can be used for non-molecular exposures as well. The pipeline will also annotate and combine results with drug target-related evidence from the literature, and has functionality to output shareable reports between investigators.

How to Install

Within R, the package can be installed for this GitHub like so:

remotes::install_github("https://github.com/jwr-git/mrpipeline")

Documentation

See here: coming soon

Docker

A docker image will also be available soon.



jwr-git/mrpipeline documentation built on Oct. 2, 2022, 3:41 p.m.