inst/app/tools/help/Profiles.md

In kmezhoud/bioCancer: Interactive Multi-Omics Cancers Data Visualization and Analysis

Show Profiles Data in Table

Profiles panel displays informations related to gene list. User needs to specify a Study, a Case, and a Genetic Profile to get the right profile.

It is more practice to select that have all data (case_all) and change only the profile.

There are in general but not always, 6 types of genetic profiles: Copy Number Alteration (CNA). mRNA expression (mRNA) Mutations (Mut) Methylation (Met): There are two probes HM_27 and HM_450 microRNA expression (miRNA) Reverse Phase Protein Array (RPPA)

It is possible to find other kind of data related to one of listed types. For example the log or z_score of mRNA expression.

Load Gene List

User can upload gene list examples or upload own gene list.

When user selects examples and clic on Load examples button, the gene list examples is loaded in DropDown Gene List.

When User selects clipboard, it is possible to copy own gene list from text file (gene symbol by line) and clic on Paste Gene List button. The gene List will be named Genes in DropDown Gene List.

Load Profiles to Datasets

It is interesting to get any statistics analysis or transformation with genetic profiles. Any table from Profiles panel can be loaded to Processing panel by checking Load Profiles to Datasets and press the button. The data frame will be named ProfData.

kmezhoud/bioCancer documentation built on Feb. 17, 2024, 10:29 a.m.