calcHitScores: Sums the pathogenicity score of allele 1 and 2 (hit score)

In luannnguyen/hmfGeneAnnotation: Determines gene amplifications and biallelic losses from HMF pipeline output

Description

Sums the pathogenicity score of allele 1 and 2 (hit score)

Usage

calcHitScores(
  gene.diplotypes,
  diplotype.origin.rank = c("cnv_cnv", "cnv_som", "cnv_germ", "som_som", "germ_som")
)

Arguments

gene.diplotypes	Table containing the mutation info of alleles 1 and 2
diplotype.origin.rank	A character vector of diplotype origins in descending order of pathogenic impact

Value

A data frame containing the hit scores and boosted hit scores (scores are boosted by order of diplotype.origin.rank to maintain priority when determining the max diplotype effect)

luannnguyen/hmfGeneAnnotation documentation built on May 6, 2020, 1:07 p.m.