hitlist: hitlist

In mgerault/mineCETSAapp: A shiny app for IMPRINTS.CETSA package

hitlist

Description

Function to categorize protein according to their Expression/Stability change based on two treatment conditions and characteristic conditions for fold change.

Usage

hitlist(
  inputdata,
  meancutoff = 0.25,
  boundedness = 4,
  qualitycutoff = 0.15,
  meandev = 0.15,
  use_prompt = TRUE,
  exported = FALSE
)

Arguments

inputdata	The input data set from which categorization is performed on and hitlist is produced from.
meancutoff	The threshold value for the mean of a triplicate(First filter of hits).
boundedness	Factor of SD/SEM, the mean needs to be within.
qualitycutoff	The threshold value for the SD/SEM to separate well-measured and illmeasured measurements.
meandev	The deviation of individual mean from the group mean in CN categorization.
use_prompt	Logical to tell if you want to use the prompt function (added for the shiny app)
exported	Logical to tell if you want to export the results. Use it when use_prompt is FALSE.

Details

This function was a first draft of hit selection from which I, Marc-Antoine Gerault, wasn't the author. After corrections and mosifications of tghe scripts, it has been kept in IMPRINTS.CETSA.app for comparison purpose but is not advised for hit selection.

Value

Dataframe of the export.

mgerault/mineCETSAapp documentation built on April 17, 2025, 7:24 p.m.