CIMICE is a tool in the field of tumor phylogenetics and its goal is to build a Markov Chain (called Cancer Progression Markov Chain, CPMC) in order to model tumor subtypes evolution. The input of CIMICE is a Mutational Matrix, so a boolean matrix representing altered genes in a collection of samples. These samples are assumed to be obtained with singlecell DNA analysis techniques and the tool is specifically written to use the peculiarities of this data for the CMPC construction.
Package details 


Bioconductor views  BiologicalQuestion GraphAndNetwork NetworkInference Phylogenetics ResearchField SingleCell Software StatisticalMethod Technology 
Maintainer  
License  Artistic2.0 
Version  0.99.5 
URL  https://github.com/redsnic/CIMICE 
Package repository  View on GitHub 
Installation 
Install the latest version of this package by entering the following in R:

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