redsnic/CIMICE: CIMICE-R: (Markov) Chain Method to Inferr Cancer Evolution

CIMICE is a tool in the field of tumor phylogenetics and its goal is to build a Markov Chain (called Cancer Progression Markov Chain, CPMC) in order to model tumor subtypes evolution. The input of CIMICE is a Mutational Matrix, so a boolean matrix representing altered genes in a collection of samples. These samples are assumed to be obtained with single-cell DNA analysis techniques and the tool is specifically written to use the peculiarities of this data for the CMPC construction.

Getting started

Package details

Bioconductor views BiologicalQuestion GraphAndNetwork NetworkInference Phylogenetics ResearchField SingleCell Software StatisticalMethod Technology
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
redsnic/CIMICE documentation built on March 30, 2022, 2:46 a.m.