import_omnipath_interactions | R Documentation |
Imports the database from https://omnipathdb.org/interactions, which contains only interactions supported by literature references. This part of the interaction database compiled a similar way as it has been presented in the first paper describing OmniPath (Turei et al. 2016).
import_omnipath_interactions(
resources = NULL,
organism = 9606,
datasets = "omnipath",
fields = NULL,
default_fields = TRUE,
references_by_resource = TRUE,
exclude = NULL,
strict_evidences = FALSE,
...
)
resources |
interactions not reported in these databases are
removed. See |
organism |
Interactions are available for human, mouse and rat. Choose among: 9606 human (default), 10116 rat and 10090 Mouse |
datasets |
Names of the interaction datasets to download: omnipath (by default). Other possiblites are: pathwayextra, kinaseextra, ligrecextra, dorothea,tf_target, mirnatarget, tf_mirna, lncrna_mrna. The user can select multiple datasets as for example: c('omnipath', 'pathwayextra', 'kinaseextra') |
fields |
The user can define here the fields to be added. If used, set the next argument, 'default_fields', to FALSE. |
default_fields |
whether to include the default fields (columns) for the query type. If FALSE, only the fields defined by the user in the 'fields' argument will be added. |
references_by_resource |
if FALSE, removes the resource name prefixes from the references (PubMed IDs); this way the information which reference comes from which resource will be lost and the PubMed IDs will be unique. |
exclude |
Character: datasets or resources to exclude. |
strict_evidences |
Logical: restrict the evidences to the queried datasets and resources. If set to FALSE, the directions and effect signs and references might be based on other datasets and resources. |
... |
optional additional arguments |
A dataframe of protein-protein interactions
get_interaction_resources
import_all_interactions
interaction_graph
print_interactions
interactions = import_omnipath_interactions(
resources = c('SignaLink3'),
organism = 9606
)
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