ramilowski_download: Downloads ligand-receptor interactions from Ramilowski et al....
In saezlab/OmnipathR: OmniPath web service client and more

ramilowski_download

R Documentation

Downloads ligand-receptor interactions from Ramilowski et al. 2015

Description

Curated ligand-receptor pairs from Supplementary Table 2 of the article "A draft network of ligand-receptor mediated multicellular signaling in human" (https://www.nature.com/articles/ncomms8866).

Usage

ramilowski_download()

Value

A data frame (tibble) with interactions.

Examples

rami_interactions <- ramilowski_download()
rami_interactions
# # A tibble: 2,557 x 16
#    Pair.Name Ligand.Approved. Ligand.Name Receptor.Approv.
#    <chr>     <chr>            <chr>       <chr>
#  1 A2M_LRP1  A2M              alpha-2-ma. LRP1
#  2 AANAT_MT. AANAT            aralkylami. MTNR1A
#  3 AANAT_MT. AANAT            aralkylami. MTNR1B
#  4 ACE_AGTR2 ACE              angiotensi. AGTR2
#  5 ACE_BDKR. ACE              angiotensi. BDKRB2
# # . with 2,547 more rows, and 12 more variables: Receptor.Name <chr>,
# #   DLRP <chr>, HPMR <chr>, IUPHAR <chr>, HPRD <chr>,
# #   STRING.binding <chr>, STRING.experiment <chr>, HPMR.Ligand <chr>,
# #   HPMR.Receptor <chr>, PMID.Manual <chr>, Pair.Source <chr>,
# #   Pair.Evidence <chr>

saezlab/OmnipathR documentation built on Nov. 10, 2024, 11:02 p.m.