regnetwork_download: Interactions from RegNetwork

In saezlab/OmnipathR: OmniPath web service client and more

Interactions from RegNetwork

Description

Downloads transcriptional and post-transcriptional regulatory interactions from the RegNetwork database (http://www.regnetworkweb.org/). The information about effect signs (stimulation or inhibition), provided by regnetwork_directions are included in the result.

Usage

regnetwork_download(organism = "human")

Arguments

organism

Character: either human or mouse.

Value

Data frame with interactions.

Examples

regn_interactions <- regnetwork_download()
regn_interactions
# # A tibble: 372,778 x 7
#    source_genesymb. source_entrez target_genesymb. target_entrez
#    <chr>            <chr>         <chr>            <chr>
#  1 USF1             7391          S100A6           6277
#  2 USF1             7391          DUSP1            1843
#  3 USF1             7391          C4A              720
#  4 USF1             7391          ABCA1            19
#  5 TP53             7157          TP73             7161
# # . with 372,768 more rows, and 3 more variables: effect <dbl>,
# #   source_type <chr>, target_type <chr>

saezlab/OmnipathR documentation built on Nov. 10, 2024, 11:02 p.m.