trrust_download: Downloads TF-target interactions from TRRUST

In saezlab/OmnipathR: OmniPath web service client and more

Downloads TF-target interactions from TRRUST

Description

TRRUST v2 (https://www.grnpedia.org/trrust/) is a database of literature mined TF-target interactions for human and mouse.

Usage

trrust_download(organism = "human")

Arguments

organism

Character: either "human" or "mouse".

Value

A data frame of TF-target interactions.

Examples

trrust_interactions <- trrust_download()
trrust_interactions
# # A tibble: 11,698 x 4
#    source_genesymbol target_genesymbol effect reference
#    <chr>             <chr>              <dbl> <chr>
#  1 AATF              BAX                   -1 22909821
#  2 AATF              CDKN1A                 0 17157788
#  3 AATF              KLK3                   0 23146908
#  4 AATF              MYC                    1 20549547
#  5 AATF              TP53                   0 17157788
#  6 ABL1              BAX                    1 11753601
#  7 ABL1              BCL2                  -1 11753601
# # . with 11,688 more rows

saezlab/OmnipathR documentation built on Nov. 10, 2024, 11:02 p.m.