update_how: Converts the count value of the given node.

In selcenari/ceRNAnetsim: Regulation Simulator of Interaction between miRNA and Competing RNAs (ceRNA)

Converts the count value of the given node.

Description

this function converts the count value of the given node.

Usage

update_how(input_graph, node_name, how, knockdown = TRUE)

Arguments

input_graph	The graph object that processed in previous step/s.
node_name	The name of the node whose count is to be changed.
how	The change in terms of fold change.
knockdown	specifies gene knockdown with default TRUE

Details

update_how function calculates the current value of given mirna or gene node on the graph object. User must specify current value as fold change.

Value

the graph object.

Examples

data('minsamp')

priming_graph(minsamp, Competing_expression, miRNA_expression)%>%
   update_how('Gene1',3)

 priming_graph(minsamp, Competing_expression, miRNA_expression,
      aff_factor = c(seed_type,energy), deg_factor = region)%>%
   update_how('Gene1', 3)

   priming_graph(minsamp, Competing_expression, miRNA_expression,
       aff_factor = c(seed_type,energy), deg_factor = region)%>%
  update_how('Gene1', how=0, knockdown= TRUE)

selcenari/ceRNAnetsim documentation built on Feb. 14, 2024, 4:20 a.m.