IntersectMatrix: Intersect genomic coordinates with matrix rows

In timoast/signac: Analysis of Single-Cell Chromatin Data

Intersect genomic coordinates with matrix rows

Description

Remove or retain matrix rows that intersect given genomic regions

Usage

IntersectMatrix(
  matrix,
  regions,
  invert = FALSE,
  sep = c("-", "-"),
  verbose = TRUE,
  ...
)

Arguments

matrix	A matrix with genomic regions in the rows
regions	A set of genomic regions to intersect with regions in the matrix. Either a vector of strings encoding the genomic coordinates, or a GRanges object.
invert	Discard rows intersecting the genomic regions supplied, rather than retain.
sep	A length-2 character vector containing the separators to be used for extracting genomic coordinates from a string. The first element will be used to separate the chromosome name from coordinates, and the second element used to separate start and end coordinates.
verbose	Display messages
...	Additional arguments passed to findOverlaps

Value

Returns a sparse matrix

Examples

counts <- matrix(data = rep(0, 12), ncol = 2)
rownames(counts) <- c("chr1-565107-565550","chr1-569174-569639",
"chr1-713460-714823","chr1-752422-753038",
"chr1-762106-763359","chr1-779589-780271")
IntersectMatrix(matrix = counts, regions = blacklist_hg19)

timoast/signac documentation built on April 5, 2024, 1:34 a.m.