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sig.pik3cags: Gene expression Grade Index (GGI) as published in Sotiriou et...

Description Usage Format Source References Examples

Description

List of 278 affymetrix hgu133a probesets representing 236 unique genes included in the PIK3CA-GS signature. The "EntrezGene.ID" column allows for mapping and "coefficient" refers to to the direction of association with PIK3CA mutation.

Usage

1

Format

sig.pik3cags is a matrix with 3 columns containing the annotations and information related to the signature itself.

Source

http://www.pnas.org/content/107/22/10208/suppl/DCSupplemental

References

Loi S, Haibe-Kains B, Majjaj S, Lallemand F, Durbecq V, Larsimont D, Gonzalez-Angulo AM, Pusztai L, Symmans FW, Bardelli A, Ellis P, Tutt AN, Gillett CE, Hennessy BT., Mills GB, Phillips WA, Piccart MJ, Speed TP, McArthur GA, Sotiriou C (2010) "PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer", Proceedings of the National Academy of Sciences, 107(22):10208–10213

Examples

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