Gene expression Grade Index (GGI) as published in Sotiriou et al. 2006

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Description

List of 278 affymetrix hgu133a probesets representing 236 unique genes included in the PIK3CA-GS signature. The "EntrezGene.ID" column allows for mapping and "coefficient" refers to to the direction of association with PIK3CA mutation.

Usage

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Format

sig.pik3cags is a matrix with 3 columns containing the annotations and information related to the signature itself.

Source

http://www.pnas.org/content/107/22/10208/suppl/DCSupplemental

References

Loi S, Haibe-Kains B, Majjaj S, Lallemand F, Durbecq V, Larsimont D, Gonzalez-Angulo AM, Pusztai L, Symmans FW, Bardelli A, Ellis P, Tutt AN, Gillett CE, Hennessy BT., Mills GB, Phillips WA, Piccart MJ, Speed TP, McArthur GA, Sotiriou C (2010) "PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer", Proceedings of the National Academy of Sciences, 107(22):10208–10213

Examples

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