Description Usage Arguments Value Author(s) Examples
This function calculates the splicing index value of two sample coverages from a NucleotideDistr
object. It is assumed that the region in the NucleotideDistr
is a single gene.
Splicing index is calculated in similar way to the implementation for exon Affy microarrays (see Gardina et al, Genome Biology, 2007 for details), but it is run for each nucleotide in the region and instead of gene-level average expression values, it uses sums of reads for both samples.
1 | getSIFromND(nd, exps)
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nd |
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exps |
a pair of numbers of samples in the experiment |
NucleotideDistr
object of type "FC" with a single vector of splicing index values
Michal Okoniewski, Anna Lesniewska
1 2 3 4 5 6 | # if (xmapConnected())
# {
# rs <- newSeqReads(1,1,20000,1)
# nd.cov <- getCoverageFromRS(rs,1:3)
# nd.fc <- getSIFromND(nd.cov,c(1,3))
# }
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