orPlot: Visualize odds ratios and p-values from SeqFeatRs assocpoint
In SeqFeatR: A Tool to Associate FASTA Sequences and Features
Description
Usage
Arguments
Details
Author(s)
See Also
Examples
Description
Creates odds ratio/p-value plots for every feature and sequence alignment position.
Usage
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orPlot(path_to_file_assocpoint_results = NULL,
save_name_pdf, separator = ";",
number_of_cases = 2, odds_column_position = c(6),
p_value_column_position = c(2), name_column_position = c(2), freq = 7,
sequence_column_position = NULL, max_y_axis = 50, interval = 10,
has_color = 0, bias = 5, p_or_od = "P")
Arguments
path_to_file_assocpoint_results
csv file with results from SeqFeatRs assocpoint function. For reference
see example file.
save_name_pdf
name of file to which results are saved in csv format.
separator
letter with which csv is separated (usually ";" or ",", or "\t").
number_of_cases
number of different features in input file.
odds_column_position
column number of first odds ratios.
p_value_column_position
column number of first p-value.
name_column_position
column number of feature name in first row.
freq
frequency of repeat in columns with more than two cases.
sequence_column_position
column number of first amino acid/nucleotide sequence.
max_y_axis
estimated guess of the best p-value/ highest Odds ratio.
Usuall the number behind the e as positive number.
interval
interval on the y axis.
has_color
if there should be presented another kind of information as
a color feature. See details.
bias
bias of colors. Select with integer values if you want the first
color further down. See details.
p_or_od
if p-values or OR should be plotted as height. "P" for p-value,
"OR" for Odds ratios.
Details
Creates from SeqFeatRs assocpoint results a graphical output where
each position in the sequence alignment is shown as bar. The height of this
bar can be the log10 of p-value at this position or the odds ratio, the
direction information (up or down) based upon odds ratio (below one is down,
above one is up). If the user adds a column number for an amino acid or DNA
base, this sequence is added above each bar.
The bar plot can be additionally colored by another type of information
(e.g. display p-values as height, odds ratio as direction and sequence
entropy as color). The source of this color information has to be added
in 'has_color' as a column number. This column can be added manually before
creating this plot. The column should contain only numbers between zero and
one. A bias can be given to change the color distribution
(see R-function colorRampPalette).
Author(s)
Bettina Budeus
See Also
Examples
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#Input file
assocpoint_result <- system.file("extdata", "assocpoint_results.csv", package="SeqFeatR")
#Usage
orPlot(
path_to_file_assocpoint_results=assocpoint_result,
save_name_pdf="orPlot.pdf",
separator=";",
number_of_cases=8,
odds_column_position=6,
p_value_column_position=2,
name_column_position=2,
freq=7,
sequence_column_position=NULL,
max_y_axis=4,
interval=0.2,
has_color=0,
bias=5,
p_or_od="P")
Example output
Loading required package: tcltk
Loading required package: tcltk2
Loading required package: Biostrings
Loading required package: BiocGenerics
Loading required package: parallel
Attaching package: ‘BiocGenerics’
The following objects are masked from ‘package:parallel’:
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from ‘package:stats’:
IQR, mad, sd, var, xtabs
The following objects are masked from ‘package:base’:
anyDuplicated, append, as.data.frame, basename, cbind, colnames,
dirname, do.call, duplicated, eval, evalq, Filter, Find, get, grep,
grepl, intersect, is.unsorted, lapply, Map, mapply, match, mget,
order, paste, pmax, pmax.int, pmin, pmin.int, Position, rank,
rbind, Reduce, rownames, sapply, setdiff, sort, table, tapply,
union, unique, unsplit, which.max, which.min
Loading required package: S4Vectors
Loading required package: stats4
Attaching package: ‘S4Vectors’
The following objects are masked from ‘package:tcltk2’:
values, values<-
The following object is masked from ‘package:base’:
expand.grid
Loading required package: IRanges
Loading required package: XVector
Attaching package: ‘Biostrings’
The following object is masked from ‘package:base’:
strsplit
Loading required package: plotrix
Warning message:
no DISPLAY variable so Tk is not available
[1] "A1"
[1] 6
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "A2"
[1] 13
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "A3"
[1] 20
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "A4"
[1] 27
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "B1"
[1] 34
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "B2"
[1] 41
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "B3"
[1] 48
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "B4"
[1] 55
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "fin"
[1] TRUE
SeqFeatR documentation built on May 2, 2019, 3:10 p.m.
R Package Documentation
Browse R Packages
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Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Description Usage Arguments Details Author(s) See Also Examples
Description
Creates odds ratio/p-value plots for every feature and sequence alignment position.
Usage
1 2 3 4 5 6 | orPlot(path_to_file_assocpoint_results = NULL,
save_name_pdf, separator = ";",
number_of_cases = 2, odds_column_position = c(6),
p_value_column_position = c(2), name_column_position = c(2), freq = 7,
sequence_column_position = NULL, max_y_axis = 50, interval = 10,
has_color = 0, bias = 5, p_or_od = "P")
|
Arguments
path_to_file_assocpoint_results |
csv file with results from SeqFeatRs assocpoint function. For reference see example file. |
save_name_pdf |
name of file to which results are saved in csv format. |
separator |
letter with which csv is separated (usually ";" or ",", or "\t"). |
number_of_cases |
number of different features in input file. |
odds_column_position |
column number of first odds ratios. |
p_value_column_position |
column number of first p-value. |
name_column_position |
column number of feature name in first row. |
freq |
frequency of repeat in columns with more than two cases. |
sequence_column_position |
column number of first amino acid/nucleotide sequence. |
max_y_axis |
estimated guess of the best p-value/ highest Odds ratio. Usuall the number behind the e as positive number. |
interval |
interval on the y axis. |
has_color |
if there should be presented another kind of information as a color feature. See details. |
bias |
bias of colors. Select with integer values if you want the first color further down. See details. |
p_or_od |
if p-values or OR should be plotted as height. "P" for p-value, "OR" for Odds ratios. |
Details
Creates from SeqFeatRs assocpoint results a graphical output where each position in the sequence alignment is shown as bar. The height of this bar can be the log10 of p-value at this position or the odds ratio, the direction information (up or down) based upon odds ratio (below one is down, above one is up). If the user adds a column number for an amino acid or DNA base, this sequence is added above each bar.
The bar plot can be additionally colored by another type of information (e.g. display p-values as height, odds ratio as direction and sequence entropy as color). The source of this color information has to be added in 'has_color' as a column number. This column can be added manually before creating this plot. The column should contain only numbers between zero and one. A bias can be given to change the color distribution (see R-function colorRampPalette).
Author(s)
Bettina Budeus
See Also
Examples
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 | #Input file
assocpoint_result <- system.file("extdata", "assocpoint_results.csv", package="SeqFeatR")
#Usage
orPlot(
path_to_file_assocpoint_results=assocpoint_result,
save_name_pdf="orPlot.pdf",
separator=";",
number_of_cases=8,
odds_column_position=6,
p_value_column_position=2,
name_column_position=2,
freq=7,
sequence_column_position=NULL,
max_y_axis=4,
interval=0.2,
has_color=0,
bias=5,
p_or_od="P")
|
Example output
Loading required package: tcltk
Loading required package: tcltk2
Loading required package: Biostrings
Loading required package: BiocGenerics
Loading required package: parallel
Attaching package: ‘BiocGenerics’
The following objects are masked from ‘package:parallel’:
clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
clusterExport, clusterMap, parApply, parCapply, parLapply,
parLapplyLB, parRapply, parSapply, parSapplyLB
The following objects are masked from ‘package:stats’:
IQR, mad, sd, var, xtabs
The following objects are masked from ‘package:base’:
anyDuplicated, append, as.data.frame, basename, cbind, colnames,
dirname, do.call, duplicated, eval, evalq, Filter, Find, get, grep,
grepl, intersect, is.unsorted, lapply, Map, mapply, match, mget,
order, paste, pmax, pmax.int, pmin, pmin.int, Position, rank,
rbind, Reduce, rownames, sapply, setdiff, sort, table, tapply,
union, unique, unsplit, which.max, which.min
Loading required package: S4Vectors
Loading required package: stats4
Attaching package: ‘S4Vectors’
The following objects are masked from ‘package:tcltk2’:
values, values<-
The following object is masked from ‘package:base’:
expand.grid
Loading required package: IRanges
Loading required package: XVector
Attaching package: ‘Biostrings’
The following object is masked from ‘package:base’:
strsplit
Loading required package: plotrix
Warning message:
no DISPLAY variable so Tk is not available
[1] "A1"
[1] 6
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "A2"
[1] 13
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "A3"
[1] 20
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "A4"
[1] 27
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "B1"
[1] 34
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "B2"
[1] 41
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "B3"
[1] 48
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "B4"
[1] 55
X A1 Corrected.p.value z.scores AA.with.lowest.p.value
1 1 0.4615384615 0.4615384615 0.0490331902 M
2 2 0.0291375291 0.0291375291 -1.774657391 P
3 3 0.0005827506 0.0005827506 -1.8950897879 D
4 4 0.0046620047 0.0046620047 -1.8778851597 T
5 5 0.4615384615 0.4615384615 0.0490331902 P
6 6 0.4615384615 0.4615384615 0.0490331902 L
7 7 0.4615384615 0.4615384615 0.0490331902 C
8 8 1 1 2.3200441025 E
9 9 0.4615384615 0.4615384615 0.0490331902 G
10 10 0.4615384615 0.4615384615 0.0490331902 G
11 11 1 1 2.3200441025 V
12 12 0.1923076923 0.1923076923 -1.086472266 Q
13 13 1 1 2.3200441025 K
14 14 0.4615384615 0.4615384615 0.0490331902 A
15 15 0.4615384615 0.4615384615 0.0490331902 S
16 16 0.4615384615 0.4615384615 0.0490331902 Y
17 17 0.1923076923 0.1923076923 -1.086472266 W
18 18 0.4615384615 0.4615384615 0.0490331902 W
19 19 0.4615384615 0.4615384615 0.0490331902 H
20 20 0.4615384615 0.4615384615 0.0490331902 G
21 21 0.4615384615 0.4615384615 0.0490331902 Q
22 22 0.4615384615 0.4615384615 0.0490331902 T
23 23 0.4615384615 0.4615384615 0.0490331902 V
24 24 0.4615384615 0.4615384615 0.0490331902 T
25 25 0.4615384615 0.4615384615 0.0490331902 N
26 26 0.1923076923 0.1923076923 -1.086472266 K
27 27 0.0005827506 0.0005827506 -1.8950897879 Q
28 28 0.4615384615 0.4615384615 0.0490331902 V
29 29 0.4615384615 0.4615384615 0.0490331902 D
30 30 1 1 2.3200441025 E
31 31 0.4615384615 0.4615384615 0.0490331902 E
32 32 0.4615384615 0.4615384615 0.0490331902 V
33 33 0.4615384615 0.4615384615 0.0490331902 P
34 34 0.4615384615 0.4615384615 0.0490331902 K
35 35 0.4615384615 0.4615384615 0.0490331902 M
36 36 0.4615384615 0.4615384615 0.0490331902 D
37 37 0.4615384615 0.4615384615 0.0490331902 E
38 38 0.4615384615 0.4615384615 0.0490331902 C
39 39 0.4615384615 0.4615384615 0.0490331902 S
40 40 0.4615384615 0.4615384615 0.0490331902 Q
Odds.ratio Wilcox ref_seq A2 Corrected.p.value.1 z.scores.1
1 Inf / L 0.2142857143 0.2142857143 0.3478774718
2 23.4961048372 / P 0.2142857143 0.2142857143 0.3478774718
3 Inf 0.05 D 0.1923076923 0.1923076923 -0.1772205988
4 0 0.05 I 0.0549450549 0.0549450549 -3.45908354
5 Inf / Q 0.2142857143 0.2142857143 0.3478774718
6 0 / G 0.2142857143 0.2142857143 0.3478774718
7 0 / N 0.2142857143 0.2142857143 0.3478774718
8 1 / E 0.2142857143 0.2142857143 0.3478774718
9 Inf / N 0.2142857143 0.2142857143 0.3478774718
10 0 / M 0.2142857143 0.2142857143 0.3478774718
11 Inf / G 0.2142857143 0.2142857143 0.3478774718
12 0 / Y 0.2142857143 0.2142857143 0.3478774718
13 Inf / Q 0.2142857143 0.2142857143 0.3478774718
14 Inf / P 0.2142857143 0.2142857143 0.3478774718
15 Inf / S 0.2142857143 0.2142857143 0.3478774718
16 0 / W 0.0934065934 0.0934065934 -2.5401619165
17 0 / I 0.2142857143 0.2142857143 0.3478774718
18 0 / F 0.2142857143 0.2142857143 0.3478774718
19 0 / C 0.2142857143 0.2142857143 0.3478774718
20 Inf / G 0.2142857143 0.2142857143 0.3478774718
21 0 / M 0.2142857143 0.2142857143 0.3478774718
22 0 / E 0.2142857143 0.2142857143 0.3478774718
23 0 / T 0.1758241758 0.1758241758 -0.5710441518
24 Inf / N 0.2142857143 0.2142857143 0.3478774718
25 Inf / G 0.2142857143 0.2142857143 0.3478774718
26 0 / S 0.2142857143 0.2142857143 0.3478774718
27 Inf 0.05 Q 0.1923076923 0.1923076923 -0.1772205988
28 Inf / C 0.1758241758 0.1758241758 -0.5710441518
29 0 / L 0.2142857143 0.2142857143 0.3478774718
30 Inf / E 0.2142857143 0.2142857143 0.3478774718
31 Inf / E 0.2142857143 0.2142857143 0.3478774718
32 Inf / M 0.2142857143 0.2142857143 0.3478774718
33 0 / F 0.2142857143 0.2142857143 0.3478774718
34 0 / H 0.2142857143 0.2142857143 0.3478774718
35 0 / C 0.2142857143 0.2142857143 0.3478774718
36 0 / C 0.2142857143 0.2142857143 0.3478774718
37 0 / W 0.032967033 0.032967033 -3.9841816106
38 0 / I 0.2142857143 0.2142857143 0.3478774718
39 0 / N 0.2142857143 0.2142857143 0.3478774718
40 0 / C 0.2142857143 0.2142857143 0.3478774718
AA.with.lowest.p.value.1 Odds.ratio.1 Wilcox.1 ref_seq.1 A3
1 V Inf / L 0.4615384615
2 W 23.4961048372 / P 0.0291375291
3 D Inf / D 0.0005827506
4 T 0 / I 0.0046620047
5 S Inf / Q 0.4615384615
6 C 0 / G 0.4615384615
7 Y 0 / N 0.4615384615
8 H 1 / E 1
9 T Inf / N 0.4615384615
10 V 0 / M 0.4615384615
11 V Inf / G 1
12 G 0 / Y 0.1923076923
13 K Inf / Q 1
14 D Inf / P 0.4615384615
15 Y Inf / S 0.4615384615
16 T 0 / W 0.4615384615
17 S 0 / I 0.1923076923
18 E 0 / F 0.4615384615
19 T 0 / C 0.4615384615
20 E Inf / G 0.4615384615
21 R 0 / M 0.4615384615
22 R 0 / E 0.4615384615
23 H 0 / T 0.4615384615
24 G Inf / N 0.4615384615
25 A Inf / G 0.4615384615
26 V 0 / S 0.1923076923
27 Q Inf / Q 0.0005827506
28 L Inf / C 0.4615384615
29 R 0 / L 0.4615384615
30 M Inf / E 1
31 N Inf / E 0.4615384615
32 A Inf / M 0.4615384615
33 Q 0 / F 0.4615384615
34 V 0 / H 0.4615384615
35 W 0 / C 0.4615384615
36 S 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 P 0 / I 0.4615384615
39 E 0 / N 0.4615384615
40 E 0 / C 0.4615384615
Corrected.p.value.2 z.scores.2 AA.with.lowest.p.value.2 Odds.ratio.2
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 P Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 C 0
8 1 2.3200441025 A 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 G Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 F Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 T Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 V Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 K Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 V 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 W 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.2 ref_seq.2 A4 Corrected.p.value.3 z.scores.3
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.3 Odds.ratio.3 Wilcox.3 ref_seq.3 B1
1 M Inf / L 0.4615384615
2 P 23.4961048372 / P 0.0291375291
3 D Inf 0.05 D 0.0005827506
4 T 0 0.05 I 0.0046620047
5 - Inf / Q 0.4615384615
6 L 0 / G 0.4615384615
7 R 0 / N 0.4615384615
8 P 1 / E 1
9 G Inf / N 0.4615384615
10 M 0 / M 0.4615384615
11 R Inf / G 1
12 Q 0 / Y 0.1923076923
13 D Inf / Q 1
14 A Inf / P 0.4615384615
15 F Inf / S 0.4615384615
16 Y 0 / W 0.4615384615
17 W 0 / I 0.1923076923
18 W 0 / F 0.4615384615
19 H 0 / C 0.4615384615
20 G Inf / G 0.4615384615
21 Q 0 / M 0.4615384615
22 T 0 / E 0.4615384615
23 V 0 / T 0.4615384615
24 M Inf / N 0.4615384615
25 N Inf / G 0.4615384615
26 K 0 / S 0.1923076923
27 Q Inf 0.05 Q 0.0005827506
28 N Inf / C 0.4615384615
29 D 0 / L 0.4615384615
30 W Inf / E 1
31 E Inf / E 0.4615384615
32 V Inf / M 0.4615384615
33 P 0 / F 0.4615384615
34 K 0 / H 0.4615384615
35 V 0 / C 0.4615384615
36 D 0 / C 0.4615384615
37 R 0 / W 0.4615384615
38 C 0 / I 0.4615384615
39 W 0 / N 0.4615384615
40 Q 0 / C 0.4615384615
Corrected.p.value.4 z.scores.4 AA.with.lowest.p.value.4 Odds.ratio.4
1 0.4615384615 0.0490331902 M Inf
2 0.0291375291 -1.774657391 P 23.4961048372
3 0.0005827506 -1.8950897879 D Inf
4 0.0046620047 -1.8778851597 T 0
5 0.4615384615 0.0490331902 - Inf
6 0.4615384615 0.0490331902 L 0
7 0.4615384615 0.0490331902 R 0
8 1 2.3200441025 G 1
9 0.4615384615 0.0490331902 G Inf
10 0.4615384615 0.0490331902 G 0
11 1 2.3200441025 V Inf
12 0.1923076923 -1.086472266 Q 0
13 1 2.3200441025 W Inf
14 0.4615384615 0.0490331902 A Inf
15 0.4615384615 0.0490331902 S Inf
16 0.4615384615 0.0490331902 Y 0
17 0.1923076923 -1.086472266 W 0
18 0.4615384615 0.0490331902 W 0
19 0.4615384615 0.0490331902 H 0
20 0.4615384615 0.0490331902 G Inf
21 0.4615384615 0.0490331902 Q 0
22 0.4615384615 0.0490331902 T 0
23 0.4615384615 0.0490331902 V 0
24 0.4615384615 0.0490331902 M Inf
25 0.4615384615 0.0490331902 N Inf
26 0.1923076923 -1.086472266 K 0
27 0.0005827506 -1.8950897879 Q Inf
28 0.4615384615 0.0490331902 N Inf
29 0.4615384615 0.0490331902 D 0
30 1 2.3200441025 E Inf
31 0.4615384615 0.0490331902 E Inf
32 0.4615384615 0.0490331902 V Inf
33 0.4615384615 0.0490331902 P 0
34 0.4615384615 0.0490331902 K 0
35 0.4615384615 0.0490331902 M 0
36 0.4615384615 0.0490331902 D 0
37 0.4615384615 0.0490331902 E 0
38 0.4615384615 0.0490331902 C 0
39 0.4615384615 0.0490331902 W 0
40 0.4615384615 0.0490331902 Q 0
Wilcox.4 ref_seq.4 B2 Corrected.p.value.5 z.scores.5
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 0.05 D 0.0005827506 0.0005827506 -1.8950897879
4 0.05 I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 0.05 Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.5 Odds.ratio.5 Wilcox.5 ref_seq.5 B3
1 M Inf / L 0.3571428571
2 P 23.4961048372 / P 0.2657342657
3 D Inf 0.05 D 0.020979021
4 T 0 0.05 I 0.030969031
5 P Inf / Q 0.1098901099
6 L 0 / G 0.3571428571
7 K 0 / N 0.1098901099
8 K 1 / E 0.3571428571
9 G Inf / N 0.2207792208
10 G 0 / M 0.1098901099
11 G Inf / G 0.3571428571
12 Q 0 / Y 0.0274725275
13 D Inf / Q 0.2582417582
14 A Inf / P 0.3571428571
15 S Inf / S 0.3571428571
16 Y 0 / W 0.1098901099
17 W 0 / I 0.3571428571
18 W 0 / F 0.3571428571
19 H 0 / C 0.3571428571
20 G Inf / G 0.3571428571
21 Q 0 / M 0.1098901099
22 T 0 / E 0.1098901099
23 V 0 / T 0.1098901099
24 T Inf / N 0.3571428571
25 N Inf / G 0.3571428571
26 K 0 / S 0.0274725275
27 V Inf 0.05 Q 0.020979021
28 N Inf / C 0.3571428571
29 D 0 / L 0.3571428571
30 K Inf / E 0.3571428571
31 E Inf / E 0.3571428571
32 V Inf / M 0.3571428571
33 P 0 / F 0.1098901099
34 K 0 / H 0.1098901099
35 M 0 / C 0.1098901099
36 D 0 / C 0.3571428571
37 W 0 / W 0.1098901099
38 C 0 / I 0.1098901099
39 S 0 / N 0.1098901099
40 Q 0 / C 0.3571428571
Corrected.p.value.6 z.scores.6 AA.with.lowest.p.value.6 Odds.ratio.6
1 0.3571428571 0.9662983254 H Inf
2 0.2657342657 0.2866957368 P 23.4961048372
3 0.020979021 -1.5330051834 D Inf
4 0.030969031 -1.4587316764 T 0
5 0.1098901099 -0.8719709716 - Inf
6 0.3571428571 0.9662983254 T 0
7 0.1098901099 -0.8719709716 R 0
8 0.3571428571 0.9662983254 P 1
9 0.2207792208 -0.0475350444 C Inf
10 0.1098901099 -0.8719709716 G 0
11 0.3571428571 0.9662983254 Q Inf
12 0.0274725275 -1.4847274039 Q 0
13 0.2582417582 0.2309906066 Q Inf
14 0.3571428571 0.9662983254 S Inf
15 0.3571428571 0.9662983254 H Inf
16 0.1098901099 -0.8719709716 Y 0
17 0.3571428571 0.9662983254 L 0
18 0.3571428571 0.9662983254 T 0
19 0.3571428571 0.9662983254 A 0
20 0.3571428571 0.9662983254 R Inf
21 0.1098901099 -0.8719709716 Q 0
22 0.1098901099 -0.8719709716 T 0
23 0.1098901099 -0.8719709716 V 0
24 0.3571428571 0.9662983254 E Inf
25 0.3571428571 0.9662983254 Q Inf
26 0.0274725275 -1.4847274039 K 0
27 0.020979021 -1.5330051834 V Inf
28 0.3571428571 0.9662983254 I Inf
29 0.3571428571 0.9662983254 H 0
30 0.3571428571 0.9662983254 A Inf
31 0.3571428571 0.9662983254 F Inf
32 0.3571428571 0.9662983254 Q Inf
33 0.1098901099 -0.8719709716 P 0
34 0.1098901099 -0.8719709716 K 0
35 0.1098901099 -0.8719709716 M 0
36 0.3571428571 0.9662983254 I 0
37 0.1098901099 -0.8719709716 E 0
38 0.1098901099 -0.8719709716 C 0
39 0.1098901099 -0.8719709716 W 0
40 0.3571428571 0.9662983254 R 0
Wilcox.6 ref_seq.6 B4 Corrected.p.value.7 z.scores.7
1 / L 0.4615384615 0.4615384615 0.0490331902
2 / P 0.0291375291 0.0291375291 -1.774657391
3 / D 0.0005827506 0.0005827506 -1.8950897879
4 / I 0.0046620047 0.0046620047 -1.8778851597
5 / Q 0.4615384615 0.4615384615 0.0490331902
6 / G 0.4615384615 0.4615384615 0.0490331902
7 / N 0.4615384615 0.4615384615 0.0490331902
8 / E 1 1 2.3200441025
9 / N 0.4615384615 0.4615384615 0.0490331902
10 / M 0.4615384615 0.4615384615 0.0490331902
11 / G 1 1 2.3200441025
12 / Y 0.1923076923 0.1923076923 -1.086472266
13 / Q 1 1 2.3200441025
14 / P 0.4615384615 0.4615384615 0.0490331902
15 / S 0.4615384615 0.4615384615 0.0490331902
16 / W 0.4615384615 0.4615384615 0.0490331902
17 / I 0.1923076923 0.1923076923 -1.086472266
18 / F 0.4615384615 0.4615384615 0.0490331902
19 / C 0.4615384615 0.4615384615 0.0490331902
20 / G 0.4615384615 0.4615384615 0.0490331902
21 / M 0.4615384615 0.4615384615 0.0490331902
22 / E 0.4615384615 0.4615384615 0.0490331902
23 / T 0.4615384615 0.4615384615 0.0490331902
24 / N 0.4615384615 0.4615384615 0.0490331902
25 / G 0.4615384615 0.4615384615 0.0490331902
26 / S 0.1923076923 0.1923076923 -1.086472266
27 / Q 0.0005827506 0.0005827506 -1.8950897879
28 / C 0.4615384615 0.4615384615 0.0490331902
29 / L 0.4615384615 0.4615384615 0.0490331902
30 / E 1 1 2.3200441025
31 / E 0.4615384615 0.4615384615 0.0490331902
32 / M 0.4615384615 0.4615384615 0.0490331902
33 / F 0.4615384615 0.4615384615 0.0490331902
34 / H 0.4615384615 0.4615384615 0.0490331902
35 / C 0.4615384615 0.4615384615 0.0490331902
36 / C 0.4615384615 0.4615384615 0.0490331902
37 / W 0.4615384615 0.4615384615 0.0490331902
38 / I 0.4615384615 0.4615384615 0.0490331902
39 / N 0.4615384615 0.4615384615 0.0490331902
40 / C 0.4615384615 0.4615384615 0.0490331902
AA.with.lowest.p.value.7 Odds.ratio.7 Wilcox.7 ref_seq.7
1 M Inf / L
2 P 23.4961048372 / P
3 D Inf 0.05 D
4 T 0 0.05 I
5 P Inf / Q
6 L 0 / G
7 R 0 / N
8 G 1 / E
9 G Inf / N
10 M 0 / M
11 K Inf / G
12 Q 0 / Y
13 T Inf / Q
14 A Inf / P
15 F Inf / S
16 Y 0 / W
17 W 0 / I
18 W 0 / F
19 H 0 / C
20 G Inf / G
21 Q 0 / M
22 T 0 / E
23 V 0 / T
24 M Inf / N
25 N Inf / G
26 K 0 / S
27 V Inf 0.05 Q
28 V Inf / C
29 D 0 / L
30 S Inf / E
31 E Inf / E
32 V Inf / M
33 P 0 / F
34 K 0 / H
35 V 0 / C
36 D 0 / C
37 W 0 / W
38 C 0 / I
39 W 0 / N
40 Q 0 / C
[1] "fin"
[1] TRUE
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