Man pages for lrstat
Power and Sample Size Calculation for Non-Proportional Hazards and Beyond
| accrual | Number of enrolled subjects |
| ad | Number of patients enrolled during an interval and having an... |
| adaptDesign | Adaptive design at an interim look |
| aml | Acute myelogenous leukemia survival data from the survival... |
| binary_tte_sim | Simulation for a binary endpoint and a time-to-event endpoint |
| BOINTable | BOIN decision table |
| caltime | Calendar times for target number of events |
| ClopperPearsonCI | Clopper-Pearson confidence interval for one-sample proportion |
| covrmst | Covariance between restricted mean survival times |
| errorSpent | Error spending |
| exitprob | Stagewise exit probabilities |
| fadjpbon | Adjusted p-values for Bonferroni-based graphical approaches |
| fadjpdun | Adjusted p-values for Dunnett-based graphical approaches |
| fadjpsim | Adjusted p-values for Simes-based graphical approaches |
| findInterval3 | Find interval numbers of indices |
| fmodmix | Adjusted p-values for modified mixture gatekeeping procedures |
| fquantile | The quantiles of a survival distribution |
| fseqbon | Group sequential trials using Bonferroni-based graphical... |
| fstdmix | Adjusted p-values for standard mixture gatekeeping procedures |
| fstp2seq | Adjusted p-values for stepwise testing procedures for two... |
| ftrunc | Adjusted p-values for Holm, Hochberg, and Hommel procedures |
| fwgtmat | Weight matrix for all intersection hypotheses |
| getAccrualDurationFromN | Accrual duration to enroll target number of subjects |
| getADCI | Confidence interval after adaptation |
| getADRCI | Repeated confidence interval after adaptation |
| getBound | Efficacy boundaries for group sequential design |
| getCI | Confidence interval after trial termination |
| getCP | Conditional power allowing for varying parameter values |
| getDesign | Power and sample size for a generic group sequential design |
| getDesignAgreement | Power and sample size for Cohen's kappa |
| getDesignANOVA | Power and sample size for one-way ANOVA |
| getDesignANOVAContrast | Power and sample size for one-way ANOVA contrast |
| getDesignEquiv | Power and sample size for a generic group sequential... |
| getDesignFisherExact | Power and sample size for Fisher's exact test for two... |
| getDesignLogistic | Power and sample size for logistic regression |
| getDesignMeanDiff | Group sequential design for two-sample mean difference |
| getDesignMeanDiffCarryover | Power and sample size for direct treatment effects in... |
| getDesignMeanDiffEquiv | Group sequential design for equivalence in two-sample mean... |
| getDesignMeanDiffMMRM | Group sequential design for two-sample mean difference from... |
| getDesignMeanDiffXO | Group sequential design for mean difference in 2x2 crossover |
| getDesignMeanDiffXOEquiv | Group sequential design for equivalence in mean difference in... |
| getDesignMeanRatio | Group sequential design for two-sample mean ratio |
| getDesignMeanRatioEquiv | Group sequential design for equivalence in two-sample mean... |
| getDesignMeanRatioXO | Group sequential design for mean ratio in 2x2 crossover |
| getDesignMeanRatioXOEquiv | Group sequential design for equivalence in mean ratio in 2x2... |
| getDesignOddsRatio | Group sequential design for two-sample odds ratio |
| getDesignOddsRatioEquiv | Group sequential design for equivalence in two-sample odds... |
| getDesignOneMean | Group sequential design for one-sample mean |
| getDesignOneMultinom | Power and sample for one-sample multinomial response |
| getDesignOneProportion | Group sequential design for one-sample proportion |
| getDesignOneRateExact | Power and sample size for one-sample Poisson rate exact test |
| getDesignOneSlope | Group sequential design for one-sample slope |
| getDesignOrderedBinom | Power and sample size for Cochran-Armitage trend test for... |
| getDesignPairedMeanDiff | Group sequential design for paired mean difference |
| getDesignPairedMeanDiffEquiv | Group sequential design for equivalence in paired mean... |
| getDesignPairedMeanRatio | Group sequential design for paired mean ratio |
| getDesignPairedMeanRatioEquiv | Group sequential design for equivalence in paired mean ratio |
| getDesignPairedPropMcNemar | Group sequential design for McNemar's test for paired... |
| getDesignRepeatedANOVA | Power and sample size for repeated-measures ANOVA |
| getDesignRepeatedANOVAContrast | Power and sample size for one-way repeated measures ANOVA... |
| getDesignRiskDiff | Group sequential design for two-sample risk difference |
| getDesignRiskDiffEquiv | Group sequential design for equivalence in two-sample risk... |
| getDesignRiskDiffExact | Power and sample size for exact unconditional test for risk... |
| getDesignRiskDiffExactEquiv | Power and sample size for exact unconditional test for... |
| getDesignRiskRatio | Group sequential design for two-sample risk ratio |
| getDesignRiskRatioEquiv | Group sequential design for equivalence in two-sample risk... |
| getDesignRiskRatioExact | Power and sample size for exact unconditional test for risk... |
| getDesignRiskRatioExactEquiv | Power and sample size for exact unconditional test for... |
| getDesignRiskRatioFM | Group sequential design for two-sample risk ratio based on... |
| getDesignSlopeDiff | Group sequential design for two-sample slope difference |
| getDesignSlopeDiffMMRM | Group sequential design for two-sample slope difference from... |
| getDesignTwoMultinom | Power and sample for difference in two-sample multinomial... |
| getDesignTwoOrdinal | Power and sample size for the Wilcoxon test for two-sample... |
| getDesignTwoWayANOVA | Power and sample size for two-way ANOVA |
| getDesignUnorderedBinom | Power and sample size for unordered multi-sample binomial... |
| getDesignUnorderedMultinom | Power and sample size for unordered multi-sample multinomial... |
| getDesignWilcoxon | Group sequential design for two-sample Wilcoxon test |
| getDurationFromNevents | Range of accrual duration for target number of events |
| getNeventsFromHazardRatio | Get the required number of events given hazard ratio |
| getRCI | Repeated confidence interval for group sequential design |
| hd | Integrated event probability over an interval with constant... |
| heart | Stanford heart transplant data from the survival package |
| hedgesg | Hedges' g effect size |
| immdef | Simulated Concorde trial data from the rpsftm package |
| kmdiff | Estimate of milestone survival difference |
| kmest | Kaplan-Meier estimates of the survival curve |
| kmpower | Power for difference in milestone survival probabilities |
| kmpower1s | Power for one-sample milestone survival probability |
| kmpowerequiv | Power for equivalence in milestone survival probability... |
| kmsamplesize | Sample size for difference in milestone survival... |
| kmsamplesize1s | Sample size for one-sample milestone survival probability |
| kmsamplesizeequiv | Sample size for equivalence in milestone survival probability... |
| kmstat | Stratified difference in milestone survival probabilities |
| kmstat1 | Milestone survival probability by stratum |
| liferegr | Parametric regression models for failure time data |
| lrpower | Log-rank test power |
| lrpowerequiv | Power for equivalence in hazard ratio |
| lrsamplesize | Log-rank test sample size |
| lrsamplesizeequiv | Sample size for equivalence in hazard ratio |
| lrsim | Log-rank test simulation |
| lrsim2e | Log-rank test simulation for two endpoints |
| lrsim2e3a | Log-rank test simulation for two endpoints and three arms |
| lrsim3a | Log-rank test simulation for three arms |
| lrstat | Number of subjects having an event and log-rank statistics |
| lrstat1 | Number of subjects having an event and log-rank statistic for... |
| lrstat-package | Power and Sample Size Calculation for Non-Proportional... |
| lrtest | Log-rank test of survival curve difference |
| mnOddsRatioCI | Miettinen-Nurminen score confidence interval for two-sample... |
| mnRateDiffCI | Miettinen-Nurminen score confidence interval for two-sample... |
| mnRateRatioCI | Miettinen-Nurminen score confidence interval for two-sample... |
| mnRiskDiffCI | Miettinen-Nurminen score confidence interval for two-sample... |
| mnRiskRatioCI | Miettinen-Nurminen score confidence interval for two-sample... |
| mTPI2Table | mTPI-2 decision table |
| natrisk | Number of subjects at risk |
| nbpower | Power for negative binomial rate ratio |
| nbpower1s | Power for one-sample negative binomial rate |
| nbpowerequiv | Power for equivalence in negative binomial rate ratio |
| nbsamplesize | Sample size for negative binomial rate ratio |
| nbsamplesize1s | Sample size for one-sample negative binomial rate |
| nbsamplesizeequiv | Sample size for equivalence in negative binomial rate ratio |
| nbstat | Negative binomial rate ratio |
| nbstat1 | Negative binomial rate ratio by stratum |
| nevent | Number of subjects having an event |
| nevent2 | Number of subjects having an event by calendar time |
| param_accrualDuration | Parameter Description: accrualDuration |
| param_accrualIntensity | Parameter Description: accrualIntensity |
| param_accrualTime | Parameter Description: accrualTime |
| param_allocationRatioPlanned | Parameter Description: allocationRatioPlanned |
| param_alpha | Parameter Description: alpha |
| param_criticalValues | Parameter Description: criticalValues |
| param_efficacyStopping | Parameter Description: efficacyStopping |
| param_estimateHazardRatio | Parameter Description: estimateHazardRatio |
| param_fixedFollowup | Parameter Description: fixedFollowup |
| param_followupTime | Parameter Description: followupTime |
| param_futilityBounds | Parameter Description: futilityBounds |
| param_futilityStopping | Parameter Description: futilityStopping |
| param_gamma | Parameter Description: gamma |
| param_gamma1 | Parameter Description: gamma1 |
| param_gamma1_stratified | Parameter Description: gamma1_stratified |
| param_gamma2 | Parameter Description: gamma2 |
| param_gamma2_stratified | Parameter Description: gamma2_stratified |
| param_hazardRatioH0 | Parameter Description: hazardRatioH0 |
| param_informationRates | Parameter Description: informationRates |
| param_kMax | Parameter Description: kMax |
| param_lambda | Parameter Description: lambda |
| param_lambda1 | Parameter Description: lambda1 |
| param_lambda1_stratified | Parameter Description: lambda1_stratified |
| param_lambda2 | Parameter Description: lambda2 |
| param_lambda2_stratified | Parameter Description: lambda2_stratified |
| param_maxFollowupTime | Parameter Description: maxFollowupTime |
| param_minFollowupTime | Parameter Description: minFollowupTime |
| param_numSubintervals | Parameter Description: numSubintervals |
| param_parameterAlphaSpending | Parameter Description: parameterAlphaSpending |
| param_parameterBetaSpending | Parameter Description: parameterBetaSpending |
| param_piecewiseSurvivalTime | Parameter Description: piecewiseSurvivalTime |
| param_rho1 | Parameter Description: rho1 |
| param_rho2 | Parameter Description: rho2 |
| param_stratumFraction | Parameter Description: stratumFraction |
| param_typeAlphaSpending | Parameter Description: typeAlphaSpending |
| param_typeBetaSpending | Parameter Description: typeBetaSpending |
| param_typeOfComputation | Parameter Description: typeOfComputation |
| param_userAlphaSpending | Parameter Description: userAlphaSpending |
| param_userBetaSpending | Parameter Description: userBetaSpending |
| patrisk | Probability of being at risk |
| pd | Integrated event probability over an interval |
| pevent | Probability of having an event |
| phregr | Proportional hazards regression model |
| powerFisherExact | Power for Fisher's exact test for two proportions |
| powerOnePropExact | Power for binomial one-sample exact test |
| powerOneRateExact | Power for Poisson one-sample exact test |
| powerRiskDiffExact | Power for exact unconditional test of risk difference |
| powerRiskDiffExactEquiv | Power for exact unconditional test of equivalence in risk... |
| powerRiskRatioExact | Power for exact unconditional test of risk ratio |
| powerRiskRatioExactEquiv | Power for exact unconditional test of equivalence in risk... |
| print.adaptDesign | Print adaptive group sequential design |
| print.BOINTable | Print the decision table for the BOIN design |
| print.design | Print group sequential design |
| print.designAgreement | Print the power and sample size for Cohen's kappa. |
| print.designANOVA | Print the power and sample size for one-way ANOVA |
| print.designANOVAContrast | Print the power and sample size for a single contrast in... |
| print.designEquiv | Print group sequential equivalence design |
| print.designLogistic | Print the power and sample size for logistic regression |
| print.designMeanDiff | Print power and sample size results for two-sample mean... |
| print.designMeanDiffCarryover | Print power and sample size results for direct treatment... |
| print.designMeanDiffEquiv | Print power and sample size results for equivalence in... |
| print.designMeanDiffMMRM | Print power and sample size results for two-sample mean... |
| print.designMeanDiffXO | Print power and sample size results for mean difference in... |
| print.designMeanDiffXOEquiv | Print power and sample size results for equivalence in mean... |
| print.designMeanRatio | Print power and sample size results for two-sample mean ratio |
| print.designMeanRatioEquiv | Print power and sample size results for equivalence in... |
| print.designMeanRatioXO | Print power and sample size results for mean ratio in 2x2... |
| print.designMeanRatioXOEquiv | Print power and sample size results for equivalence in mean... |
| print.designOddsRatio | Print power and sample size results for two-sample odds ratio |
| print.designOddsRatioEquiv | Print power and sample size results for equivalence in... |
| print.designOneMean | Print power and sample size results for one-sample mean |
| print.designOneMultinom | Print the power and sample size for one-sample multinomial... |
| print.designOneProportion | Print power and sample size results for one-sample proportion |
| print.designOneSlope | Print power and sample size results for one-sample slope |
| print.designOrderedBinom | Print the power and sample size for Cochran-Armitage trend... |
| print.designPairedMeanDiff | Print power and sample size results for paired mean... |
| print.designPairedMeanDiffEquiv | Print power and sample size results for equivalence in paired... |
| print.designPairedMeanRatio | Print power and sample size results for paired mean ratio |
| print.designPairedMeanRatioEquiv | Print power and sample size results for equivalence in paired... |
| print.designPairedPropMcNemar | Print power and sample size results for McNemar's test for... |
| print.designRepeatedANOVA | Print the power and sample size for one-way repeated measures... |
| print.designRepeatedANOVAContrast | Print the power and sample size for a single contrast in... |
| print.designRiskDiff | Print power and sample size results for two-sample risk... |
| print.designRiskDiffEquiv | Print power and sample size results for equivalence in... |
| print.designRiskRatio | Print power and sample size results for two-sample risk ratio |
| print.designRiskRatioEquiv | Print power and sample size results for equivalence in... |
| print.designRiskRatioFM | Print power and sample size results for two-sample risk ratio... |
| print.designSlopeDiff | Print power and sample size results for two-sample slope... |
| print.designSlopeDiffMMRM | Print power and sample size results for two-sample slope... |
| print.designTwoMultinom | Print the power and sample size for difference in two-sample... |
| print.designTwoOrdinal | Print the power and sample size for Wilcoxon test for... |
| print.designTwoWayANOVA | Print the power and sample size for two-way ANOVA |
| print.designUnorderedBinom | Print the power and sample size for unordered multi-sample... |
| print.designUnorderedMultinom | Print the power and sample size for unordered multi-sample... |
| print.designWilcoxon | Print power and sample size results for two-sample Wilcoxon... |
| print.estimateCI | Print the point estimate and confidence interval |
| print.kmpower | Print power and sample size results for milestone survival... |
| print.kmpower1s | Print power and sample size results for one-sample milestone... |
| print.kmpowerequiv | Print power and sample size results for equivalence in... |
| print.lrpower | Print power and sample size results for log-rank tests |
| print.lrpowerequiv | Print power and sample size results for equivalence in hazard... |
| print.lrsim | Print simulation results for log-rank tests |
| print.mTPI2Table | Print the decision table for the mTPI-2 design |
| print.nbpower | Print power and sample size results for negative binomial... |
| print.nbpower1s | Print power and sample size results for one-sample negative... |
| print.nbpowerequiv | Print power and sample size results for equivalence in... |
| print.rmpower | Print power and sample size results for restricted mean... |
| print.rmpower1s | Print power and sample size results for one-sample restricted... |
| print.rmpowerequiv | Print power and sample size results for equivalence in... |
| ptpwexp | Distribution function of truncated piecewise exponential... |
| pwexpcuts | Piecewise exponential approximation to a survival... |
| pwexploglik | Profile log-likelihood function for the change points in... |
| qtpwexp | Quantile function of truncated piecewise exponential... |
| rawdata | A simulated time-to-event data set with 10 replications |
| remlOddsRatio | REML estimates of individual proportions with specified odds... |
| remlRateDiff | REML estimates of individual rates with specified rate... |
| remlRateRatio | REML estimates of individual rates with specified rate ratio |
| remlRiskDiff | REML estimates of individual proportions with specified risk... |
| remlRiskRatio | REML estimates of individual proportions with specified risk... |
| repeatedPValue | Repeated p-values for group sequential design |
| riskDiffExactCI | Exact unconditional confidence interval for risk difference |
| riskDiffExactPValue | P-value for exact unconditional test of risk difference |
| riskRatioExactCI | Exact unconditional confidence interval for risk ratio |
| riskRatioExactPValue | P-value for exact unconditional test of risk ratio |
| rmdiff | Estimate of restricted mean survival time difference |
| rmest | Estimate of restricted mean survival time |
| rmpower | Power for difference in restricted mean survival times |
| rmpower1s | Power for one-sample restricted mean survival time |
| rmpowerequiv | Power for equivalence in restricted mean survival time... |
| rmsamplesize | Sample size for difference in restricted mean survival times |
| rmsamplesize1s | Sample size for one-sample restricted mean survival time |
| rmsamplesizeequiv | Sample size for equivalence in restricted mean survival time... |
| rmst | Restricted mean survival time |
| rmstat | Stratified difference in restricted mean survival times |
| rmstat1 | Restricted mean survival time by stratum |
| rpsft | Rank preserving structured failure time model (RPSFTM) for... |
| rtpwexp | Random number generation function of truncated piecewise... |
| runShinyApp | Run Shiny app |
| samplesizeFisherExact | Sample size for Fisher's exact test for two proportions |
| samplesizeOnePropExact | Sample size for binomial one-sample exact test |
| samplesizeOneRateExact | Sample size for Poisson one-sample exact test |
| samplesizeRiskDiffExact | Sample size for exact unconditional test of risk difference |
| samplesizeRiskDiffExactEquiv | Sample size for exact unconditional test of equivalence in... |
| samplesizeRiskRatioExact | Sample size for exact unconditional test of risk ratio |
| samplesizeRiskRatioExactEquiv | Sample size for exact unconditional test of equivalence in... |
| simon2stage | Simon's two-stage design |
| simonBayesAnalysis | Analysis of Simon's Bayesian basket trials |
| simonBayesSim | Simulation of Simon's Bayesian basket trials |
| survQuantile | Brookmeyer-Crowley confidence interval for quantiles of... |
| tobin | Tobin's tobit data from the survival package |
| updateGraph | Update graph for graphical approaches |
| zstatOddsRatio | Miettinen-Nurminen score test statistic for two-sample odds... |
| zstatRateDiff | Miettinen-Nurminen score test statistic for two-sample rate... |
| zstatRateRatio | Miettinen-Nurminen score test statistic for two-sample rate... |
| zstatRiskDiff | Miettinen-Nurminen score test statistic for two-sample risk... |
| zstatRiskRatio | Miettinen-Nurminen score test statistic for two-sample risk... |
