| accrual | Number of Enrolled Subjects |
| ad | Number of Patients Enrolled During an Interval and Having an... |
| adaptDesign | Adaptive Design at an Interim Look |
| aml | Acute myelogenous leukemia survival data from the survival... |
| binary_tte_sim | Simulation for a Binary and a Time-to-Event Endpoint in Group... |
| BOINTable | BOIN Decision Table for Dose-Finding Trials |
| caltime | Calendar Times for Target Number of Events |
| ClopperPearsonCI | Clopper-Pearson Confidence Interval for One-Sample Proportion |
| covrmst | Covariance Between Restricted Mean Survival Times |
| errorSpent | Error Spending |
| exitprob | Stagewise Exit Probabilities |
| fadjpbon | Adjusted p-Values for Bonferroni-Based Graphical Approaches |
| fadjpdun | Adjusted p-Values for Dunnett-Based Graphical Approaches |
| fadjpsim | Adjusted p-Values for Simes-Based Graphical Approaches |
| findInterval3 | Find Interval Numbers of Indices |
| float_to_fraction | Converting a decimal to a fraction |
| fmodmix | Adjusted p-Values for Modified Mixture Gatekeeping Procedures |
| fquantile | The Quantiles of a Survival Distribution |
| fseqbon | Group Sequential Trials Using Bonferroni-Based Graphical... |
| fstdmix | Adjusted p-Values for Standard Mixture Gatekeeping Procedures |
| fstp2seq | Adjusted p-Values for Stepwise Testing Procedures for Two... |
| ftrunc | Adjusted p-Values for Holm, Hochberg, and Hommel Procedures |
| fwgtmat | Weight Matrix for All Intersection Hypotheses |
| getAccrualDurationFromN | Accrual Duration to Enroll Target Number of Subjects |
| getADCI | Confidence Interval After Adaptation |
| getADRCI | Repeated Confidence Interval After Adaptation |
| getBound | Efficacy Boundaries for Group Sequential Design |
| getCI | Confidence Interval After Trial Termination |
| getCP | Conditional Power Allowing for Varying Parameter Values |
| getDesign | Power and Sample Size for a Generic Group Sequential Design |
| getDesignAgreement | Power and Sample Size for Cohen's kappa |
| getDesignANOVA | Power and Sample Size for One-Way ANOVA |
| getDesignANOVAContrast | Power and Sample Size for One-Way ANOVA Contrast |
| getDesignEquiv | Power and Sample Size for a Generic Group Sequential... |
| getDesignFisherExact | Power and Sample Size for Fisher's Exact Test for Two... |
| getDesignLogistic | Power and Sample Size for Logistic Regression |
| getDesignMeanDiff | Group Sequential Design for Two-Sample Mean Difference |
| getDesignMeanDiffCarryover | Power and Sample Size for Direct Treatment Effects in... |
| getDesignMeanDiffCarryoverEquiv | Power and Sample Size for Equivalence in Direct Treatment... |
| getDesignMeanDiffEquiv | Group Sequential Design for Equivalence in Two-Sample Mean... |
| getDesignMeanDiffMMRM | Group Sequential Design for Two-Sample Mean Difference From... |
| getDesignMeanDiffXO | Group Sequential Design for Mean Difference in 2x2 Crossover |
| getDesignMeanDiffXOEquiv | Group Sequential Design for Equivalence in Mean Difference in... |
| getDesignMeanRatio | Group Sequential Design for Two-Sample Mean Ratio |
| getDesignMeanRatioEquiv | Group Sequential Design for Equivalence in Two-Sample Mean... |
| getDesignMeanRatioXO | Group Sequential Design for Mean Ratio in 2x2 Crossover |
| getDesignMeanRatioXOEquiv | Group Sequential Design for Equivalence in Mean Ratio in 2x2... |
| getDesignOddsRatio | Group Sequential Design for Two-Sample Odds Ratio |
| getDesignOddsRatioEquiv | Group Sequential Design for Equivalence in Two-Sample Odds... |
| getDesignOneMean | Group Sequential Design for One-Sample Mean |
| getDesignOneMultinom | Power and Sample Size for One-Sample Multinomial Response |
| getDesignOneProportion | Group Sequential Design for One-Sample Proportion |
| getDesignOneRateExact | Power and Sample Size for One-Sample Poisson Rate Exact Test |
| getDesignOneSlope | Group Sequential Design for One-Sample Slope |
| getDesignOrderedBinom | Power and Sample Size for Cochran-Armitage Trend Test for... |
| getDesignPairedMeanDiff | Group Sequential Design for Paired Mean Difference |
| getDesignPairedMeanDiffEquiv | Group Sequential Design for Equivalence in Paired Mean... |
| getDesignPairedMeanRatio | Group Sequential Design for Paired Mean Ratio |
| getDesignPairedMeanRatioEquiv | Group Sequential Design for Equivalence in Paired Mean Ratio |
| getDesignPairedPropMcNemar | Group Sequential Design for McNemar's Test for Paired... |
| getDesignRepeatedANOVA | Power and Sample Size for Repeated-Measures ANOVA |
| getDesignRepeatedANOVAContrast | Power and Sample Size for One-Way Repeated Measures ANOVA... |
| getDesignRiskDiff | Group Sequential Design for Two-Sample Risk Difference |
| getDesignRiskDiffEquiv | Group Sequential Design for Equivalence in Two-Sample Risk... |
| getDesignRiskDiffExact | Power and Sample Size for Exact Unconditional Test for Risk... |
| getDesignRiskDiffExactEquiv | Power and Sample Size for Exact Unconditional Test for... |
| getDesignRiskRatio | Group Sequential Design for Two-Sample Risk Ratio |
| getDesignRiskRatioEquiv | Group Sequential Design for Equivalence in Two-Sample Risk... |
| getDesignRiskRatioExact | Power and Sample Size for Exact Unconditional Test for Risk... |
| getDesignRiskRatioExactEquiv | Power and Sample Size for Exact Unconditional Test for... |
| getDesignRiskRatioFM | Group Sequential Design for Two-Sample Risk Ratio Based on... |
| getDesignSlopeDiff | Group Sequential Design for Two-Sample Slope Difference |
| getDesignSlopeDiffMMRM | Group Sequential Design for Two-Sample Slope Difference From... |
| getDesignTwoMultinom | Power and Sample Size for Difference in Two-Sample... |
| getDesignTwoOrdinal | Power and Sample Size for the Wilcoxon Test for Two-Sample... |
| getDesignTwoWayANOVA | Power and Sample Size for Two-Way ANOVA |
| getDesignUnorderedBinom | Power and Sample Size for Unordered Multi-Sample Binomial... |
| getDesignUnorderedMultinom | Power and Sample Size for Unordered Multi-Sample Multinomial... |
| getDesignWilcoxon | Group Sequential Design for Two-Sample Wilcoxon Test |
| getDurationFromNevents | Range of Accrual Duration for Target Number of Events |
| getNeventsFromHazardRatio | Required Number of Events Given Hazard Ratio |
| getRCI | Repeated Confidence Interval for Group Sequential Design |
| hazard_pd | Hazard Function for Progressive Disease (PD) |
| hazard_sub | Hazard Function for Sub Population |
| hd | Integrated Event Probability Over an Interval With Constant... |
| heart | Stanford heart transplant data from the survival package |
| hedgesg | Hedges' g Effect Size |
| immdef | Simulated CONCORDE trial data from the rpsftm package |
| ingots | The binary data from Cox and Snell (1989, pp. 10-11). |
| kmdiff | Estimate of Milestone Survival Difference |
| kmest | Kaplan-Meier Estimates of Survival Curve |
| kmpower | Power for Difference in Milestone Survival Probabilities |
| kmpower1s | Power for One-Sample Milestone Survival Probability |
| kmpowerequiv | Power for Equivalence in Milestone Survival Probability... |
| kmsamplesize | Sample Size for Difference in Milestone Survival... |
| kmsamplesize1s | Sample Size for One-Sample Milestone Survival Probability |
| kmsamplesizeequiv | Sample Size for Equivalence in Milestone Survival Probability... |
| kmstat | Stratified Difference in Milestone Survival Probabilities |
| kmstat1 | Milestone Survival Probability by Stratum |
| kmsurv | Kaplan-Meier Survival Probability Based on Pooled Sample |
| liferegr | Parametric Regression Models for Failure Time Data |
| logisregr | Logistic Regression Models for Binary Data |
| lrpower | Log-Rank Test Power |
| lrpowerequiv | Power for Equivalence in Hazard Ratio |
| lrsamplesize | Log-Rank Test Sample Size |
| lrsamplesizeequiv | Sample Size for Equivalence in Hazard Ratio |
| lrschoenfeld | Schoenfeld Method for Log-Rank Test Sample Size Calculation |
| lrsim | Log-Rank Test Simulation |
| lrsim2e | Log-Rank Test Simulation for Two Endpoints |
| lrsim2e3a | Log-Rank Test Simulation for Two Endpoints and Three Arms |
| lrsim3a | Log-Rank Test Simulation for Three Arms |
| lrsimsub | Log-Rank Test Simulation for Enrichment Design |
| lrstat | Number of Subjects Having an Event and Log-Rank Statistics |
| lrstat1 | Number of Subjects Having an Event and Log-Rank Statistic for... |
| lrstat-package | Power and Sample Size Calculation for Non-Proportional... |
| lrtest | Log-Rank Test of Survival Curve Difference |
| mnOddsRatioCI | Miettinen-Nurminen Score Confidence Interval for Two-Sample... |
| mnRateDiffCI | Miettinen-Nurminen Score Confidence Interval for Two-Sample... |
| mnRateRatioCI | Miettinen-Nurminen Score Confidence Interval for Two-Sample... |
| mnRiskDiffCI | Miettinen-Nurminen Score Confidence Interval for Two-Sample... |
| mnRiskRatioCI | Miettinen-Nurminen Score Confidence Interval for Two-Sample... |
| mTPI2Table | mTPI-2 Decision Table |
| natrisk | Number of Subjects at Risk |
| nbpower | Power for Negative Binomial Rate Ratio |
| nbpower1s | Power for One-Sample Negative Binomial Rate |
| nbpowerequiv | Power for Equivalence in Negative Binomial Rate Ratio |
| nbsamplesize | Sample Size for Negative Binomial Rate Ratio |
| nbsamplesize1s | Sample Size for One-Sample Negative Binomial Rate |
| nbsamplesizeequiv | Sample Size for Equivalence in Negative Binomial Rate Ratio |
| nbstat | Negative Binomial Rate Ratio |
| nbstat1 | Negative Binomial Rate Ratio by Stratum |
| nevent | Number of Subjects Having an Event |
| nevent2 | Number of Subjects Having an Event by Calendar Time |
| param_accrualDuration | Parameter Description: accrualDuration |
| param_accrualIntensity | Parameter Description: accrualIntensity |
| param_accrualTime | Parameter Description: accrualTime |
| param_allocationRatioPlanned | Parameter Description: allocationRatioPlanned |
| param_alpha | Parameter Description: alpha |
| param_criticalValues | Parameter Description: criticalValues |
| param_efficacyStopping | Parameter Description: efficacyStopping |
| param_estimateHazardRatio | Parameter Description: estimateHazardRatio |
| param_fixedFollowup | Parameter Description: fixedFollowup |
| param_followupTime | Parameter Description: followupTime |
| param_futilityBounds | Parameter Description: futilityBounds |
| param_futilityStopping | Parameter Description: futilityStopping |
| param_gamma | Parameter Description: gamma |
| param_gamma1 | Parameter Description: gamma1 |
| param_gamma1_stratified | Parameter Description: gamma1_stratified |
| param_gamma2 | Parameter Description: gamma2 |
| param_gamma2_stratified | Parameter Description: gamma2_stratified |
| param_hazardRatioH0 | Parameter Description: hazardRatioH0 |
| param_informationRates | Parameter Description: informationRates |
| param_kMax | Parameter Description: kMax |
| param_lambda | Parameter Description: lambda |
| param_lambda1 | Parameter Description: lambda1 |
| param_lambda1_stratified | Parameter Description: lambda1_stratified |
| param_lambda2 | Parameter Description: lambda2 |
| param_lambda2_stratified | Parameter Description: lambda2_stratified |
| param_maxFollowupTime | Parameter Description: maxFollowupTime |
| param_minFollowupTime | Parameter Description: minFollowupTime |
| param_parameterAlphaSpending | Parameter Description: parameterAlphaSpending |
| param_parameterBetaSpending | Parameter Description: parameterBetaSpending |
| param_piecewiseSurvivalTime | Parameter Description: piecewiseSurvivalTime |
| param_rho1 | Parameter Description: rho1 |
| param_rho2 | Parameter Description: rho2 |
| param_stratumFraction | Parameter Description: stratumFraction |
| param_typeAlphaSpending | Parameter Description: typeAlphaSpending |
| param_typeBetaSpending | Parameter Description: typeBetaSpending |
| param_typeOfComputation | Parameter Description: typeOfComputation |
| param_userAlphaSpending | Parameter Description: userAlphaSpending |
| param_userBetaSpending | Parameter Description: userBetaSpending |
| patrisk | Probability of Being at Risk |
| pbvnorm | Distribution Function of the Standard Bivariate Normal |
| pd | Integrated Event Probability Over an Interval |
| pevent | Probability of Having an Event |
| phregr | Proportional Hazards Regression Models |
| powerFisherExact | Power for Fisher's Exact Test for Two Proportions |
| powerOnePropExact | Power for Binomial One-Sample Exact Test |
| powerOneRateExact | Power for Poisson One-Sample Exact Test |
| powerRiskDiffExact | Power for Exact Unconditional Test of Risk Difference |
| powerRiskDiffExactEquiv | Power for Exact Unconditional Test of Equivalence in Risk... |
| powerRiskRatioExact | Power for Exact Unconditional Test of Risk Ratio |
| powerRiskRatioExactEquiv | Power for Exact Unconditional Test of Equivalence in Risk... |
| print.adaptDesign | Print Adaptive Group Sequential Design |
| print.BOINTable | Print the Decision Table for the BOIN Design |
| print.design | Print Group Sequential Design |
| print.designAgreement | Print Power and Sample Size Results for Cohen's kappa. |
| print.designANOVA | Print Power and Sample Size Results for One-Way ANOVA |
| print.designANOVAContrast | Print Power and Sample Size Results for a Single Contrast in... |
| print.designEquiv | Print Group Sequential Equivalence Design |
| print.designLogistic | Print Power and Sample Size Results for Logistic Regression |
| print.designMeanDiff | Print Power and Sample Size Results for Two-Sample Mean... |
| print.designMeanDiffCarryover | Print Power and Sample Size Results for Direct Treatment... |
| print.designMeanDiffCarryoverEquiv | Print Power and Sample Size Results for Equivalence in Direct... |
| print.designMeanDiffEquiv | Print Power and Sample Size Results for Equivalence in... |
| print.designMeanDiffMMRM | Print Power and Sample Size Results for Two-Sample Mean... |
| print.designMeanDiffXO | Print Power and Sample Size Results for Mean Difference in... |
| print.designMeanDiffXOEquiv | Print Power and Sample Size Results for Equivalence in Mean... |
| print.designMeanRatio | Print Power and Sample Size Results for Two-Sample Mean Ratio |
| print.designMeanRatioEquiv | Print Power and Sample Size Results for Equivalence in... |
| print.designMeanRatioXO | Print Power and Sample Size Results for Mean Ratio in 2x2... |
| print.designMeanRatioXOEquiv | Print Power and Sample Size Results for Equivalence in Mean... |
| print.designOddsRatio | Print Power and Sample Size Results for Two-Sample Odds Ratio |
| print.designOddsRatioEquiv | Print Power and Sample Size Results for Equivalence in... |
| print.designOneMean | Print Power and Sample Size Results for One-Sample Mean |
| print.designOneMultinom | Print Power and Sample Size Results for One-Sample... |
| print.designOneProportion | Print Power and Sample Size Results for One-Sample Proportion |
| print.designOneSlope | Print Power and Sample Size Results for One-Sample Slope |
| print.designOrderedBinom | Print Power and Sample Size Results for Cochran-Armitage... |
| print.designPairedMeanDiff | Print Power and Sample Size Results for Paired Mean... |
| print.designPairedMeanDiffEquiv | Print Power and Sample Size Results for Equivalence in Paired... |
| print.designPairedMeanRatio | Print Power and Sample Size Results for Paired Mean Ratio |
| print.designPairedMeanRatioEquiv | Print Power and Sample Size Results for Equivalence in Paired... |
| print.designPairedPropMcNemar | Print Power and Sample Size Results for McNemar's Test for... |
| print.designRepeatedANOVA | Print Power and Sample Size Results for One-Way Repeated... |
| print.designRepeatedANOVAContrast | Print Power and Sample Size Results for a Single Contrast in... |
| print.designRiskDiff | Print Power and Sample Size Results for Two-Sample Risk... |
| print.designRiskDiffEquiv | Print Power and Sample Size Results for Equivalence in... |
| print.designRiskRatio | Print Power and Sample Size Results for Two-Sample Risk Ratio |
| print.designRiskRatioEquiv | Print Power and Sample Size Results for Equivalence in... |
| print.designRiskRatioFM | Print Power and Sample Size Results for Two-Sample Risk Ratio... |
| print.designSlopeDiff | Print Power and Sample Size Results for Two-Sample Slope... |
| print.designSlopeDiffMMRM | Print Power and Sample Size Results for Two-Sample Slope... |
| print.designTwoMultinom | Print Power and Sample Size Results for Difference in... |
| print.designTwoOrdinal | Print Power and Sample Size Results for Wilcoxon Test for... |
| print.designTwoWayANOVA | Print Power and Sample Size Results for Two-Way ANOVA |
| print.designUnorderedBinom | Print Power and Sample Size Results for Unordered... |
| print.designUnorderedMultinom | Print Power and Sample Size Results for Unordered... |
| print.designWilcoxon | Print Power and Sample Size Results for Two-Sample Wilcoxon... |
| print.estimateCI | Print the Point Estimate and Confidence Interval |
| print.kmpower | Print Power and Sample Size Results for Milestone Survival... |
| print.kmpower1s | Print Power and Sample Size Results for One-Sample Milestone... |
| print.kmpowerequiv | Print Power and Sample Size Results for Equivalence in... |
| print.liferegr | Print liferegr Object |
| print.logisregr | Print logisregr Object |
| print.lrpower | Print Power and Sample Size Results for Log-Rank Tests |
| print.lrpowerequiv | Print Power and Sample Size Results for Equivalence in Hazard... |
| print.lrsim | Print Simulation Results for Log-Rank Tests |
| print.mTPI2Table | Print the Decision Table for the mTPI-2 Design |
| print.nbpower | Print Power and Sample Size Results for Negative Binomial... |
| print.nbpower1s | Print Power and Sample Size Results for One-Sample Negative... |
| print.nbpowerequiv | Print Power and Sample Size Results for Equivalence in... |
| print.phregr | Print phregr Object |
| print.rmpower | Print Power and Sample Size Results for Restricted Mean... |
| print.rmpower1s | Print Power and Sample Size Results for One-Sample Restricted... |
| print.rmpowerequiv | Print Power and Sample Size Results for Equivalence in... |
| ptpwexp | Distribution Function of Truncated Piecewise Exponential... |
| pwexpcuts | Piecewise Exponential Approximation to a Survival... |
| pwexploglik | Profile Log-Likelihood Function for Change Points in... |
| qrcpp | QR Decomposition of a Matrix |
| qtpwexp | Quantile Function of Truncated Piecewise Exponential... |
| rawdata | A simulated time-to-event data set with 10 replications |
| remlOddsRatio | REML Estimates of Individual Proportions With Specified Odds... |
| remlRateDiff | REML Estimates of Individual Rates With Specified Rate... |
| remlRateRatio | REML Estimates of Individual Rates With Specified Rate Ratio |
| remlRiskDiff | REML Estimates of Individual Proportions With Specified Risk... |
| remlRiskRatio | REML Estimates of Individual Proportions With Specified Risk... |
| repeatedPValue | Repeated p-Values for Group Sequential Design |
| residuals_liferegr | Residuals for Parametric Regression Models for Failure Time... |
| residuals_phregr | Residuals for Proportional Hazards Regression Models |
| riskDiffExactCI | Exact Unconditional Confidence Interval for Risk Difference |
| riskDiffExactPValue | P-Value for Exact Unconditional Test of Risk Difference |
| riskRatioExactCI | Exact Unconditional Confidence Interval for Risk Ratio |
| riskRatioExactPValue | P-Value for Exact Unconditional Test of Risk Ratio |
| rmdiff | Estimate of Restricted Mean Survival Time Difference |
| rmest | Estimate of Restricted Mean Survival Time |
| rmpower | Power for Difference in Restricted Mean Survival Times |
| rmpower1s | Power for One-Sample Restricted Mean Survival Time |
| rmpowerequiv | Power for Equivalence in Restricted Mean Survival Time... |
| rmsamplesize | Sample Size for Difference in Restricted Mean Survival Times |
| rmsamplesize1s | Sample Size for One-Sample Restricted Mean Survival Time |
| rmsamplesizeequiv | Sample Size for Equivalence in Restricted Mean Survival Time... |
| rmst | Restricted Mean Survival Time |
| rmstat | Stratified Difference in Restricted Mean Survival Times |
| rmstat1 | Restricted Mean Survival Time by Stratum |
| rmvnorm | Random Multivariate Normal Generation |
| rtpwexp | Random Number Generation Function of Truncated Piecewise... |
| runShinyApp_lrstat | Run Shiny App |
| samplesizeFisherExact | Sample Size for Fisher's Exact Test for Two Proportions |
| samplesizeOnePropExact | Sample Size for Binomial One-Sample Exact Test |
| samplesizeOneRateExact | Sample Size for Poisson One-Sample Exact Test |
| samplesizeRiskDiffExact | Sample Size for Exact Unconditional Test of Risk Difference |
| samplesizeRiskDiffExactEquiv | Sample Size for Exact Unconditional Test of Equivalence in... |
| samplesizeRiskRatioExact | Sample Size for Exact Unconditional Test of Risk Ratio |
| samplesizeRiskRatioExactEquiv | Sample Size for Exact Unconditional Test of Equivalence in... |
| sexagg | Urinary tract infection data from the logistf package |
| shilong | The randomized clinical trial SHIVA data in long format from... |
| simon2stage | Simon's Two-Stage Design |
| simonBayesAnalysis | Analysis of Simon's Bayesian Basket Trials |
| simonBayesSim | Simulation of Simon's Bayesian Basket Trials |
| six | The repeated measures data from the "Six Cities" study of the... |
| survfit_phregr | Survival Curve for Proportional Hazards Regression Models |
| survQuantile | Brookmeyer-Crowley Confidence Interval for Quantiles of... |
| survsplit | Split a survival data set at specified cut points |
| svdcpp | Singular Value Decomposition of a Matrix |
| tobin | Tobin's tobit data from the survival package |
| updateGraph | Update Graph for Graphical Approaches |
| zstatOddsRatio | Miettinen-Nurminen Score Test Statistic for Two-Sample Odds... |
| zstatRateDiff | Miettinen-Nurminen Score Test Statistic for Two-Sample Rate... |
| zstatRateRatio | Miettinen-Nurminen Score Test Statistic for Two-Sample Rate... |
| zstatRiskDiff | Miettinen-Nurminen Score Test Statistic for Two-Sample Risk... |
| zstatRiskRatio | Miettinen-Nurminen Score Test Statistic for Two-Sample Risk... |
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