find_robust_zscore_hit: Title Find robust Z-score Hit

In EmanuelSoda/ScreenR: Package to Perform High Throughput Biological Screening

Title Find robust Z-score Hit

Description

Title Find robust Z-score Hit

Usage

find_robust_zscore_hit(table_treate_vs_control, number_barcode)

Arguments

table_treate_vs_control	A table computed with the function compute_data_table. It contain for each barcode the associated Gene the counts in the treated and control and the value for the Log2FC, Zscore, ZscoreRobust in each day.
number_barcode	Number of barcode that as to be differentially expressed (DE)in order to consider the gene associated DE. Example a gene is associated with 10 shRNA we consider a gene DE if it has at least number_barcode = 5 shRNA DE.

Value

Return a tibble containing the hit for the robust Z-score

Examples

object <- get0("object", envir = asNamespace("ScreenR"))
table <- compute_metrics(object,
    control = "TRT", treatment = "Time3",
    day = "Time3"
)
result <- find_robust_zscore_hit(table, number_barcode = 6)
head(result)

EmanuelSoda/ScreenR documentation built on Sept. 29, 2023, 12:33 a.m.