Man pages for Sterniii3/drugdevelopR
Utility-Based Optimal Phase II/III Drug Development Planning
| d3_skipII_tte | Expected probability to go to phase III for time-to-event... |
| dbivanorm | Density of the bivariate normal distribution |
| drugdevelopR | Utility based optimal phase II/III drug development planning |
| drugdevelopResult | Construct a drugdevelopResult object from a data frame |
| Ed3_bias | Expected sample size for phase III for bias adjustment... |
| Ed3_tte | Expected sample size for phase III for time-to-event outcomes |
| En3_bias_binary | Expected sample size for phase III for bias adjustment... |
| En3_bias_normal | Expected sample size for phase III for bias adjustment... |
| Epgo23 | Expected probability to do third phase III trial |
| Epgo23_binary | Expected probability to do third phase III trial |
| Epgo23_normal | Expected probability to do third phase III trial |
| Epgo_bias | Expected probability to go to phase III for bias adjustment... |
| Epgo_bias_binary | Expected probability to go to phase III for bias adjustment... |
| Epgo_bias_normal | Expected probability to go to phase III for bias adjustment... |
| Epgo_tte | Expected probability to go to phase III for time-to-event... |
| EPsProg23 | Expected probability of a successful program deciding between... |
| EPsProg23_binary | Expected probability of a successful program deciding between... |
| EPsProg23_normal | Expected probability of a successful program deciding between... |
| EPsProg_bias | Expected probability of a successful program for bias... |
| EPsProg_bias_binary | Expected probability of a successful program for bias... |
| EPsProg_bias_normal | Expected probability of a successful program for bias... |
| EPsProg_multiple_normal | Expected probability of a successful program for multiple... |
| EPsProg_multiple_tte | Expected probability of a successful program for multiple... |
| EPsProg_multitrial | Expected probability of a successful program for multitrial... |
| EPsProg_multitrial_binary | Expected probability of a successful program for multitrial... |
| EPsProg_multitrial_normal | Expected probability of a successful program for multitrial... |
| EPsProg_tte | Expected probability of a successful program for... |
| Ess_binary | Expected sample size for phase III for multiarm programs with... |
| Ess_multiple_normal | Expected sample size for phase III for multiple endpoints... |
| Ess_multiple_tte | Expected sample size for phase III for multiple endpoints... |
| Ess_normal | Expected sample size for phase III for multiarm programs with... |
| Ess_tte | Expected sample size for phase III for multiarm programs with... |
| fmax | Density for the maximum of two normally distributed random... |
| fmin | Density for the minimum of two normally distributed random... |
| get_sample_multiple_normal | Generate sample for Monte Carlo integration in the multiple... |
| get_sample_multiple_tte | Generate sample for Monte Carlo integration in the multiple... |
| optimal_bias | Optimal phase II/III drug development planning for... |
| optimal_bias_binary | Optimal phase II/III drug development planning when... |
| optimal_bias_generic | Generic function for optimizing drug development programs... |
| optimal_bias_normal | Optimal phase II/III drug development planning when... |
| optimal_binary | Optimal phase II/III drug development planning with binary... |
| optimal_binary_generic | Generic function for optimizing programs with binary... |
| optimal_generic | Generic function for optimizing drug development programs |
| optimal_multiarm | Optimal phase II/III drug development planning for multi-arm... |
| optimal_multiarm_binary | Optimal phase II/III drug development planning for multi-arm... |
| optimal_multiarm_generic | Generic function for optimizing multi-arm programs |
| optimal_multiarm_normal | Optimal phase II/III drug development planning for multi-arm... |
| optimal_multiple_generic | Generic function for optimizing drug development programs... |
| optimal_multiple_normal | Optimal phase II/III drug development planning for programs... |
| optimal_multiple_tte | Optimal phase II/III drug development planning for programs... |
| optimal_multitrial | Optimal phase II/III drug development planning where several... |
| optimal_multitrial_binary | Optimal phase II/III drug development planning where several... |
| optimal_multitrial_generic | Generic function for optimizing multi-trial programs |
| optimal_multitrial_normal | Optimal phase II/III drug development planning where several... |
| optimal_normal | Optimal phase II/III drug development planning with normally... |
| optimal_normal_generic | Generic function for optimizing normally distributed... |
| optimal_return_doc | Function for generating documentation of return values |
| optimal_tte | Optimal phase II/III drug development planning with... |
| optimal_tte_generic | Generic function for optimal planning of time-to-event... |
| os_tte | Probability that endpoint OS significant |
| pgo_binary | Probability to go to phase III for multiarm programs with... |
| pgo_multiple_normal | Probability to go to phase III for multiple endpoints with... |
| pgo_multiple_tte | Probability to go to phase III for multiple endpoints in the... |
| pgo_normal | Probability to go to phase III for multiarm programs with... |
| pgo_tte | Probability to go to phase III for multiarm programs with... |
| posp_normal | Probability of a successful program, when going to phase III... |
| print.drugdevelopResult | Printing a drugdevelopResult Object |
| print_drugdevelopResult_helper | Helper function for printing a drugdevelopResult Object |
| prior_tte | Prior distribution for time-to-event outcomes |
| PsProg_binary | Probability of a successful program for multiarm programs... |
| PsProg_normal | Probability of a successful program for multiarm programs... |
| PsProg_tte | Probability of a successful program for multiarm programs... |
| pw | Probabilty that effect in endpoint one is larger than in... |
| ss_binary | Total sample size for phase III trial with l treatments and... |
| ss_normal | Total sample size for phase III trial with l treatments and... |
| ss_tte | Total sample size for phase III trial with l treatments and... |
| utility23 | Utility function for multitrial programs deciding between two... |
| utility23_binary | Utility function for multitrial programs deciding between two... |
| utility23_normal | Utility function for multitrial programs deciding between two... |
| utility_bias | Utility function for bias adjustment programs with... |
| utility_bias_binary | Utility function for bias adjustment programs with binary... |
| utility_bias_normal | Utility function for bias adjustment programs with normally... |
| utility_multiarm | Utility function for multiarm programs with time-to-event... |
| utility_multiarm_binary | Utility function for multiarm programs with binary... |
| utility_multiarm_normal | Utility function for multiarm programs with normally... |
| utility_multiple_normal | Utility function for multiple endpoints with normally... |
| utility_multiple_tte | Utility function for multiple endpoints in a... |
| utility_multitrial | Utility function for multitrial programs in a time-to-event... |
| utility_multitrial_binary | Utility function for multitrial programs with binary... |
| utility_multitrial_normal | Utility function for multitrial programs with normally... |
| utility_tte | Utility function for time-to-event outcomes. |
