calc_dcorr_GC_content_logfc: calc_dcorr_GC_content_logfc
In alex-kalinka-cruk/fgcQC: QC metric calculations for CRISPR screen data produced at the FGC
Description
Usage
Arguments
Value
Author(s)
References
View source: R/calc_dcorr_GC_content_logfc.R
Description
Calculates the distance correlation between the log2 fold change and the GC content of sgRNAs in a given library.
Usage
1
calc_dcorr_GC_content_logfc(logfc, library, col_suffix)
Arguments
logfc
A data frame of log2 fold change data for a sample contrast (e.g. Control vs Plasmid; gRNAs as rows) as generated by 'fgcQC::calc_log2_fold_change_gRNAs'.
library
A data frame containing the library file in which the first column gives the sgRNA sequence and the second column gives the sgRNA ID.
col_suffix
A character string providing a name to go at the end of the output column name (e.g. 'ctrl_plasmid').
Value
A data frame with a 'SampleName' column and a 'distcorr_GC_content_logfc' column.
Author(s)
Alex T. Kalinka, alex.kalinka@cancer.org.uk
References
Szekely, G.J., Rizzo, M.L., and Bakirov, N.K. (2007), Measuring and Testing Dependence by Correlation of Distances, Annals of Statistics, Vol. 35 No. 6, pp. 2769-2794.
alex-kalinka-cruk/fgcQC documentation built on June 23, 2020, 9:05 p.m.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Description Usage Arguments Value Author(s) References
View source: R/calc_dcorr_GC_content_logfc.R
Description
Calculates the distance correlation between the log2 fold change and the GC content of sgRNAs in a given library.
Usage
1 | calc_dcorr_GC_content_logfc(logfc, library, col_suffix)
|
Arguments
logfc |
A data frame of log2 fold change data for a sample contrast (e.g. Control vs Plasmid; gRNAs as rows) as generated by 'fgcQC::calc_log2_fold_change_gRNAs'. |
library |
A data frame containing the library file in which the first column gives the sgRNA sequence and the second column gives the sgRNA ID. |
col_suffix |
A character string providing a name to go at the end of the output column name (e.g. 'ctrl_plasmid'). |
Value
A data frame with a 'SampleName' column and a 'distcorr_GC_content_logfc' column.
Author(s)
Alex T. Kalinka, alex.kalinka@cancer.org.uk
References
Szekely, G.J., Rizzo, M.L., and Bakirov, N.K. (2007), Measuring and Testing Dependence by Correlation of Distances, Annals of Statistics, Vol. 35 No. 6, pp. 2769-2794.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Embedding an R snippet on your website
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.