calc_mahalanobis_dist_plasmid: calc_mahalanobis_dist_plasmid

In alex-kalinka-cruk/fgcQC: QC metric calculations for CRISPR screen data produced at the FGC

Description

Calculates the Mahalanobis distance ratio for control vs plasmid and treatment vs plasmid.

Usage

calc_mahalanobis_dist_plasmid(
  counts,
  plasmid_sample_id,
  control_sample_id,
  treat_sample_id
)

Arguments

counts	A data frame of normalized counts for each sample in the study (samples as columns, gRNAs as rows).
plasmid_sample_id	A character vector naming the plasmid sample(s).
control_sample_id	A character vector naming the control sample(s).
treat_sample_id	A character vector naming the treatment sample(s). Ignored if 'NULL'.

Value

A data frame with the following column(s): ‘mahalanobis_dist_ratio.<comp>' where ’<comp>' is one of 'ctrl_plasmid' or 'treat_plasmid'.

Author(s)

Alex T. Kalinka, [e-mail]

alex-kalinka-cruk/fgcQC documentation built on June 23, 2020, 9:05 p.m.