calc_dispersion_adj_gRNA: calc_dispersion_adj_gRNA
In alex-kalinka-cruk/fgcQC: QC metric calculations for CRISPR screen data produced at the FGC
Description
Usage
Arguments
Author(s)
References
View source: R/calc_dispersion_adj_gRNA.R
Description
Calculates adjusted dispersion estimates at the gRNA level using a shrinkage estimator and returns the mean across all gRNAs for the Control vs Treatment comparison.
Usage
1
calc_dispersion_adj_gRNA(counts, control_sample_id, treat_sample_id)
Arguments
counts
A data frame of normalized counts for each sample in the study (samples as columns, gRNAs as rows).
control_sample_id
A character vector naming one or more control samples.
treat_sample_id
A character vector naming one or more treatment samples. If 'NULL' then there are no treatment samples.
Author(s)
Alex T. Kalinka, alex.kalinka@cancer.org.uk
References
Wu, H. et al. 2013. A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data. Biostatistics 14: 232-243.
alex-kalinka-cruk/fgcQC documentation built on June 23, 2020, 9:05 p.m.
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Description Usage Arguments Author(s) References
View source: R/calc_dispersion_adj_gRNA.R
Description
Calculates adjusted dispersion estimates at the gRNA level using a shrinkage estimator and returns the mean across all gRNAs for the Control vs Treatment comparison.
Usage
1 | calc_dispersion_adj_gRNA(counts, control_sample_id, treat_sample_id)
|
Arguments
counts |
A data frame of normalized counts for each sample in the study (samples as columns, gRNAs as rows). |
control_sample_id |
A character vector naming one or more control samples. |
treat_sample_id |
A character vector naming one or more treatment samples. If 'NULL' then there are no treatment samples. |
Author(s)
Alex T. Kalinka, alex.kalinka@cancer.org.uk
References
Wu, H. et al. 2013. A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data. Biostatistics 14: 232-243.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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