normalize_library_depth_median_ratio: normalize_library_depth_median_ratio
In alex-kalinka-cruk/fgcQC: QC metric calculations for CRISPR screen data produced at the FGC
Description
Usage
Arguments
Value
Author(s)
References
View source: R/normalize_library_depth_median_ratio.R
Description
Normalizes library depth from a counts file using the median-ratio method [1].
Usage
1
Arguments
counts
A data frame of counts for each sample in the study (samples as columns, gRNAs as rows).
Value
A data frame in which the sample columns are library-depth normalized.
Author(s)
Alex T. Kalinka, alex.kalinka@cancer.org.uk
References
Wang T, Wei JJ, Sabatini DM, Lander ES. Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014, 343: 80-84.
Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol. 2010, 11: R106
alex-kalinka-cruk/fgcQC documentation built on June 23, 2020, 9:05 p.m.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Description Usage Arguments Value Author(s) References
View source: R/normalize_library_depth_median_ratio.R
Description
Normalizes library depth from a counts file using the median-ratio method [1].
Usage
1 |
Arguments
counts |
A data frame of counts for each sample in the study (samples as columns, gRNAs as rows). |
Value
A data frame in which the sample columns are library-depth normalized.
Author(s)
Alex T. Kalinka, alex.kalinka@cancer.org.uk
References
Wang T, Wei JJ, Sabatini DM, Lander ES. Genetic screens in human cells using the CRISPR-Cas9 system. Science. 2014, 343: 80-84. Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol. 2010, 11: R106
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Embedding an R snippet on your website
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.