bowang-lab/simATAC: This package is a single-cell ATAC-seq simulator

This package provides a set of functions to simulate single-cell ATAC-seq count matrix from real single-cell samples, highly resembling real scATAC-seq datasets in library size, sparsity, and averaged chromatin accessibility signals. simATAC estimates the parameters of statistical distributions fitted to the main parameters, and generates the final synthetic counts using the estimated models.

install.packages("remotes")
remotes::install_github("bowang-lab/simATAC")