simATACEstBinMean: Estimate bin coverage mean

In bowang-lab/simATAC: This package is a single-cell ATAC-seq simulator

Description

Estimate the coefficients of second degree polynomial function between bins' non-zero cell proportions and means.

Usage

simATACEstBinMean(count, object)

Arguments

count	A sparse count matrix to estimate parameters from.
object	simATACCount object to store estimated parameters.

Details

Parameters for the second degree polynomial function between bin means and bin non-zero cell proportion are estimated by using lm and poly. simATAC excludes bins having non-zero cell proportion more than 0.8 in modelling the polynomial function.

Value

simATACCount object with updated polynomial function parameters.

bowang-lab/simATAC documentation built on Jan. 28, 2021, 1:22 a.m.