Description Usage Arguments Value
View source: R/aracne-ap_viper.R
Run fgsea on each regulon set individually
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 | fgsea_ssgsea_msviper(
mra,
mra_stat = "p.value",
genome_prefix,
msigdb_species = "Homo sapiens",
msigdb_cat = "H",
tag,
exprdh,
tx2gene,
gene_col = "external_gene_name",
output_dir,
sig_val = 0.1,
per_regulon = NULL,
phenos
)
|
mra |
msviper class object with es, ledge |
mra_stat |
statistic used to rank data, comes from msViper |
genome_prefix |
string of a genome in biomart$dataset, suffixed with '_gene_ensembl' |
msigdb_species |
one of msigdbr::msigdbr_species(), default:"Homo sapiens" |
msigdb_cat |
one of 'c("H", paste0("C", c(1:7)))', see: gsea-msigdb.org/gsea/msigdb/collections.jsp |
tag |
string used to prefix output |
exprdh |
expression data |
tx2gene |
annotation data |
gene_col |
the name of the column in tibble with gene names found in pathways, set to "rownames" if they are the rownames (default) |
output_dir |
path to where output goes |
sig_val |
significance used in analysis |
per_regulon |
flag to indicate if fgsea is at collective regulon level, or if each regulon and the genes it is co-expressed with are used |
phenos |
metadata tibble |
sure
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