RNAseq.fpkms: RNAseq derived genome-wide basal expression profiles for 15...

In francescojm/CRISPRcleanR: Unsupervised correction of gene independent cell responses to CRISPR-cas9 targeting

RNAseq derived genome-wide basal expression profiles for 15 cell lines.

Description

Genome-wide substitute reads with fragments per kilobase of exon per million reads mapped (FPKM) for the 15 cell lines specified in CL.subset, derived from a comprehensive collection of RNAseq profiles described in [1] and used in [2] to assess CRISPRcleaneR results.

Usage

data(RNAseq.fpkms)

Format

A data frame with one bservations per gene and one variable per cell line. Row names indicates HGNC symbols and column names indicate cell line COSMIC identifiers [3].

References

[1] Garcia-Alonso L, Iorio F, Matchan A, et al. Transcription factor activities enhance markers of drug response in cancer doi: https://doi.org/10.1101/129478

[2] Iorio, F., Behan, F. M., Goncalves, E., Beaver, C., Ansari, R., Pooley, R., et al. (n.d.). Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting.
http://doi.org/10.1101/228189

[3] Forbes SA, Beare D, Boutselakis H, et al. COSMIC: somatic cancer genetics at high-resolution Nucleic Acids Research, Volume 45, Issue D1, 4 January 2017, Pages D777-D783,

See Also

CL.subset

Examples

data(RNAseq.fpkms)
head(RNAseq.fpkms)

francescojm/CRISPRcleanR documentation built on April 30, 2023, 5:41 a.m.