HotNet: HotNet Class

Description Usage Arguments Value

Description

Represents the results of a HotNet analysis

HotNet constructor

Usage

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HotNet(gene.scores, version = c("2009", "2012", "2013"), delta = 1e-04,
  fdr = 0.25, permutations = 100, auto.delta = F)

Arguments

gene.scores

data.frame where the first column contains gene names and the second column contains scores representing the proportion of samples in which the gene is mutated.

version

Version of ReactomeFI network (2009, 2012, 2013).

delta

HotNet delta value

fdr

False discovery rate threshold

permutations

Number of permutations. Largest value is 1000.

auto.delta

If true, algorithm will select a delta value. This option will make the analysis take more time to finish.

Value

HotNet HotNet S4 object containing the results of HotNet analysis. These results should be filtered before using them to generate a network


funnell/reactomefi documentation built on May 16, 2019, 4:05 p.m.