Determine which clones are subclone or founder clone or both or none subclones are identified based on cellular fractions of the ancestor clones. Eg. if a clone is a subclone, all of its decendent clones are subclone. If a clone is not a subclone and has zero cell frac, its only decendent clone is not a subclone founder clones are identified as clones whose cell frac is non-zero and whose parent has zero cell frac
1 | determine.subclone(v, r)
|
v: |
data frame of subclonal structure as output of enumerate.clones v must have row.names = v$lab |
r: |
label of the clone where it and its decendent clones will be evaluated. This is often the root of the tree |
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