get_ddd_variants_for_gene: loads the variants for a given gene from source VCFs

In jeremymcrae/recessiveStats: Enrichment of recessive variants within genes

Description

loads the variants for a given gene from source VCFs

Usage

get_ddd_variants_for_gene(hgnc, chrom, start = NULL, end = NULL,
  probands = NULL, check_last_base = FALSE)

Arguments

hgnc	hgnc symbol as character string
chrom	chromosome as character string
start	start position of region to be investigated (if checking for gene region defined by chromosome coordinates rather than a HGNC-based gene region).
end	end position of region to be investigated (if checking for gene region defined by chromosome coordinates rather than a HGNC-based gene region).
probands	vector of IDs for probands for the gene, or NULL
check_last_base	boolean for whether to check if last base non-lofs can be LoF.

Value

dataframe of variants

jeremymcrae/recessiveStats documentation built on May 19, 2019, 5:08 a.m.