Description Usage Arguments Value Examples
View source: R/alleles_recessive_test.R
test enrichment of inherited biallelic LoF and compound heterozygous LoF/Func
1 | lof_func_enrichment(freq, count, cohort_n, autozygosity = 0)
|
freq |
list of cumulative frequencies of variation in a population for rare LoF variants, and rare functional variants. |
count |
number of probands with inherited variants in the gene. |
cohort_n |
number of probands in population. |
autozygosity |
rate of autozygosity in the cohort being investigated. |
P-value from testing for biallelic LoF and Lof/Func variants.
1 2 3 | freq = list(lof=0.001, functional=0.1)
count = 3
lof_func_enrichment(freq, count, 1000)
|
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