ccube_m6: Run Ccube with model 6: Normal-Binomial. TODO: to be removed...

View source: R/ccube.R

ccube_m6R Documentation

Run Ccube with model 6: Normal-Binomial. TODO: to be removed in the final release

Description

Run Ccube with model 6: Normal-Binomial. TODO: to be removed in the final release

Usage

ccube_m6(mydata, epi = 0.001, init = 2, prior = NULL, tol = 1e-20,
  maxiter = 1000, fit_mult = F, fit_hyper = T, use = c("use_base",
  "use_one"), verbose = FALSE)

Arguments

mydata

mutation data frame

epi

sequencing error

init

scalar number of clusters, or vector all possible cluster numbers

prior

prior parameters

tol

VBEM convergence threshold

maxiter

VBEM maximum iteration

fit_mult

whether or not to estimate multiplicities

fit_hyper

whether or not to estimat hyperparameters

use

methods to get rough estimates of ccf

verbose

show progress

Value

a list containing model parameters


keyuan/ccube documentation built on Jan. 11, 2023, 12:01 a.m.