methyl_master_sesame: ##methyl_master_sesame

View source: R/methyl_master_sesame.R

methyl_master_sesameR Documentation

##methyl_master_sesame

Description

MethylMasteR run SeSAMe function

Usage

methyl_master_sesame(
  sesame.idat.files.dir = NULL,
  sesame.output.dir = NULL,
  sesame.ref = NULL,
  sesame.sample.sheet.path = NULL,
  sesame.comparison = NULL,
  sesame.file.sep = NULL,
  sesame.data.cache = "EPIC",
  sesame.data.normal = "EPIC.5.normal",
  sesame.genome.version = "hg38",
  sesame.reference = "internal",
  sesame.split.by = NULL,
  sesame.save.seg = FALSE,
  ...
)

Arguments

sesame.idat.files.dir

The input directory for the sesame routine

sesame.output.dir

The ouptut directory for the sesame routine

sesame.sample.sheet.path

The path to the MethylMaster sample sheet

sesame.comparison

the 2-element vector of Sample_Group levels to be compared. First element is taken as the treatment and second as the control if "reference" is set to "internal" the second element is ignored

sesame.file.sep

the file separator to use

sesame.data.cache

the sesame data cache to use

sesame.data.normal

the sesame normal data set to use, e.g. Epic.5.Normal

sesame.genome.version

the sesame reference version (default is hg38)

sesame.reference

the sesame reference to use

sesame.split.by

which column, if any, to split the analyses by

sesame.save.seg

save the segmentation results as .RData object

...

additional parameters to passs to methyl_master_sesame

Value

A seg object for downstream analysis


mmariani123/MethylMasteR documentation built on June 22, 2022, 3:06 p.m.