A query alignment and a file specifying which hla_genotypes should be checked for different patients are first compared to construct a list of scores that must be computed. This list is then passed to the score_all_epitopes function which computes the scores. The results and error logs are then returned as output.
1 2 3 4 5 6 7 8 | match_epitopes(
query_alignment,
patient_hla,
lanl_hla_data,
range_expansion = 5,
update_progress_bar = NULL,
substitutionMatrix = "BLOSUM50"
)
|
query_alignment |
The query alignment |
patient_hla |
The data.frame (of class Patient_HLA) that contain lists all the HLA genotypes each patient has. |
lanl_hla_data |
The data.frame (of class LANL_HLA_data) that contains the descriptions of the different HLA genotypes |
range_expansion |
After the epitope is found in the reference seqeuence, search in each of the query sequences for the same epitope, but expand the range with this number of amino acids |
update_progress_bar |
A closure passed in from a reactive shiny expression that allows a progress bar to be updated when using the shiny web ui. |
substitutionMatrix |
substitution matrix representing the fixed substitution scores for an alignment. It cannot be used in conjunction with ‘patternQuality’ and ‘subjectQuality’ arguments. |
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.