computeExprGroup_antagonist: Modeling the effect of antagonist on the ligand-receptor...

In sqjin/CellChat: Inference and analysis of cell-cell communication from single-cell and spatial transcriptomics data

Modeling the effect of antagonist on the ligand-receptor interaction

Description

Modeling the effect of antagonist on the ligand-receptor interaction

Usage

computeExprGroup_antagonist(
  data.use,
  pairLRsig,
  cofactor_input,
  group,
  index.antagonist,
  Kh,
  FunMean,
  n
)

Arguments

data.use	data matrix
pairLRsig	the L-R interactions
cofactor_input	the cofactor_input from CellChatDB
group	a factor defining the cell groups
index.antagonist	the index of antagonist in the database
Kh	a parameter in Hill function
FunMean	the function for computing mean expression per group
n	Hill coefficient

sqjin/CellChat documentation built on Nov. 10, 2023, 4:29 a.m.