music.iter.ct | R Documentation |

Scaling bulk data and signature matrix and estimate cell type proportion

```
music.iter.ct(
Y,
D,
S,
Sigma.ct,
iter.max = 1000,
nu = 1e-04,
eps = 0.01,
centered = FALSE,
normalize = FALSE
)
```

`Y` |
vector of bulk tissue expression |

`S` |
vector of Avg. Library size |

`Sigma.ct` |
matrix of Subject level variation with cross-cell-type covariance. |

`iter.max` |
numeric, maximum iteration number. Default is 1000 |

`nu` |
regulation parameter, take care of weight when taking recipical by default nu = 0.0001. |

`eps` |
Threshold of convergence. Default is 0.01. |

`centered` |
logic, subtract avg of Y and D. Default is FALSE. |

`normalize` |
logic, divide Y and D by their standard deviation. Default is FALSE |

`X` |
matrix, Signature matrix |

a list same as nnls.weight.basic

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