custom_regulons_calc: Quantifying TF activity using a data frame of custom regulons...

In zcollest/scRegNetwrapper: Wrapper functions for single cell regulatory network analysis (DoRothEA, PROGENy, pySCENIC) as well as tools for downstream analysis and method comparisons.

Description

This function uses VIPER to quantify TF activity given a data frame of custom regulons and returns a Seurat object assay with the results.

Usage

custom_regulons_calc(seurat_obj, regulons, assay_name, cores = 16)

Arguments

seurat_obj	seurat object
regulons	data frame of custom regulons (must be same format as DoRothEA regulons)
assay_name	string to name the resulting Seurat object assay
cores	number of cores to use for calculation (default is 16)

Examples

custom_regulons_calc(data,regulons,"custom_TFactivity"))

zcollest/scRegNetwrapper documentation built on Dec. 23, 2021, 9:14 p.m.