run_dorothea: Quantifying TF activity from DoRothEA Regulons

In zcollest/scRegNetwrapper: Wrapper functions for single cell regulatory network analysis (DoRothEA, PROGENy, pySCENIC) as well as tools for downstream analysis and method comparisons.

Description

Takes a Seurat object and a vector of DoRothEA confidence levels and returns the same Seurat object with a "dorothea" assay of TF activity scores.

Usage

run_dorothea(seurat_obj, conf_scores, cores = 16)

Arguments

seurat_obj	Seurat object
conf_scores	vector of DoRothEA confidence scores (A,B,C,D,E)
cores	number of cores to use for calculation (default = 16)

Examples

run_dorothea(pbmc10k, c("A","B","C","D"),cores=20)

zcollest/scRegNetwrapper documentation built on Dec. 23, 2021, 9:14 p.m.