Smooth the hits of neighboring fragments

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Description

Counts are transformed to a hit if they exceed the given threshold. Hits are then smoothed using the number of fragments provided by binWidth. binWidth has to be an odd number so that an equal number of fragments to each side of the current fragment are used for smoothing.

Usage

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smoothHitPerCent(object, binWidth = 101, thresh = 1)

Arguments

object

A FourC object.

binWidth

Integer vector of odd numbers.

thresh

Single integer defining the threshold for calling a fragment a hit.

Value

Returns an updated FourC object with smoothed counts for each binWidth as new assays.

Author(s)

Felix A. Klein, felix.klein@embl.de

See Also

FourC

Examples

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data(fc, package="FourCSeq")

fc <- smoothHitPerCent(fc)
fc