FourCSeq is an R package dedicated to the analysis of (multiplexed) 4C sequencing data. The package provides a pipeline to detect specific interactions between DNA elements and identify differential interactions between conditions. The statistical analysis in R starts with individual bam files for each sample as inputs. To obtain these files, the package contains a python script (extdata/python/demultiplex.py) to demultiplex libraries and trim off primer sequences. With a standard alignment software the required bam files can be then be generated.
|Author||Felix A. Klein, EMBL Heidelberg|
|Bioconductor views||Preprocessing Sequencing Software|
|Maintainer||Felix A. Klein <[email protected]>|
|License||GPL (>= 3)|
|Package repository||View on Bioconductor|
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