Uses quadratic programming for signature refitting, i.e., to decompose the mutation catalog from an individual tumor sample into a set of given mutational signatures (either Alexandrov-model signatures or Shiraishi-model signatures), computing weights that reflect the contributions of the signatures to the mutation load of the tumor.
|Author||Rosario M. Piro [aut, cre], Sandra Krueger [ctb]|
|Bioconductor views||BiologicalQuestion BiomedicalInformatics DNASeq Genetics GenomicVariation SNP Sequencing Software SomaticMutation StatisticalMethod|
|Maintainer||Rosario M. Piro <[email protected]>|
|Package repository||View on Bioconductor|
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