Compute Contrasts from Linear Model Fit

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Description

Given a linear model fit to microarray data, compute estimated coefficients and standard errors for a given set of contrasts. This function was adapted from contrasts.fit of the limma package.

Usage

1

Arguments

fit

an MArrayLM object or a list object produced by the function lm.series or equivalent.

contrasts

numeric matrix with row corresponding to coefficients in fit and columns containing contrasts. May be a vector if there is only one contrast.

Details

This function was adapted from the equivalent contrasts.fit limma's function to do the linear model fit without use the empirical Bayes method given by the function eBayes.

Value

The result of this function is an object of class MArrayLM.

Author(s)

Gustavo H. Esteves <gesteves@vision.ime.usp.br>, adapted from the limma's function.

See Also

lmFit, contrasts.fit, eBayes, MArrayLM.

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